cytochrome

cytochrome

1. Using a structural model of the cytochrome b protein as a template, we divided cyt b sequence data for species within Anserifomes into three functional domains.

3）序列具有较高的转换/颠换比，基因序列中的转换与颠换都未饱和，序列中的碱基组成高度偏倚；

2. Furthore, Bax translocation, cytochrome c release, and caspase 9 activation wereblocked by Z-VAD.

Bax的膜转移、细胞色素C的释放以及Caspase 8,9的激活都可被Caspase广谱抑制剂Z-VAD.

3. Cytochrome c oxidase subunite V

cox5

4. cytochrome c oxidase subunit gene (coxl)

coxl

5. Cytochrome C oxidase subunit Ⅰ

COⅠ基因

6. CYP2B6 is an important cytochrome P450 enzymes and contributes to metabolism of about 7% of therapeutically usual drugs,including some with narrow therapeutic index.

CYP2B6是一个在药理和毒理学上均占有重要地位的代谢酶,参与约7%临床上常用药物代谢,其中包括一些治疗窗较窄的药物。

7. Cytochrome P450 2D6 (CYP2D6) is an important hepatic microsomal enzyme which metabolizes clinical drugs.

CYP2D6在临床重要药物代谢中具有重要作用。

8. D-Lactate dehydrogenase cytochrome

D-乳酸脱氢酶(细胞色素)

9. L-Lactate dehydrogenase(cytochrome)

L-乳酸脱氢酶(细胞色素)

10. NADH - cytochrome b5 reductase

NADH-细胞色素b5还原酶

11. NADPH cytochrome C reductase

NADPH细胞色素C还原酶

12. Plasmid pMD18-histamine cytochrome P450

pMD18-HP450

13. PRN can obviously shorten hypnotic duration of pentobarbital sodium, which suggests that PRN could induce liver microsomal cytochrome P450 in mice.

PRN能显著缩短戊巴比妥钠对小鼠的催眠时间 ,提示PRN能诱导小鼠肝微粒体细胞色素P4 5 0活性

14. Expression of a wheat cytochrome P450 monooxygenase in yeast and its inhibition by glyphosate.

Wen-Sheng Xiang, Xiang-Jing Wang, Tian-Rui Ren（通讯作者） & Xiu-Lian Ju.

15. Pyruvate dehydrogenase(cytochrome)

丙酮酸脱氢酶(细胞色素)

16. Pyruvate dehydrogenase cytochrome measurement

丙酮酸脱氢酶细胞色素测量

17. After 1,4,7,10,14 days of exposure,the rats were killed,whole lung RNA were isolated and cytochrome b mRNA were detected with reverse transcription polymerase chain reaction(RT-PCR).

两组分别于高氧或空气暴露后1、4、7、10和14d时提取肺组织RNA,采用半定量逆转录聚合酶链反应(RT-PCR)测定Cytb mRNA表达;

18. Ethanol is maily metabolized in liver by ethanol dehydrogenase,cytochrome P450-2E1 and acetaldehyde dehydrogenase.Ethanol metabolic enzyme plays an important role in the metabolism of ethanol.

乙醇在肝内主要由乙醇脱氢酶、细胞色素P450-2E1和乙醛脱氢酶代谢,乙醇代谢酶在乙醇代谢过程中发挥着最重要的作用。

19. Lactic acid dehydrogenase(cytochrome)

乳酸脱氢酶(细胞色素)

20. Keywords schizandrin;metabolism;sex difference;cytochrome P450;liver microsome;

五味子醇甲;代谢;性别差异;细胞色素P450;肝微粒体;

21. Nitrite reductase(cytochrome)

亚硝酸还原酶(细胞色素)

22. human cytochrome P450 reductase

人细胞色素P450还原酶

23. The data indicate that EGCG has a protective effect on the injury of PC12 cells induced by PQ, which may be related to downregulating the over-expression of cytochrome c in the cytosol.

以上结果提示EGCG可减轻PQ诱导的PC12细胞损伤,其机制可能与下调细胞色素c在胞浆内的过表达有关。

24. The enzymes involved in alcohol metabolism include mainly alcohol dehydrogenase(ADH), aldehyde dehydrogenase(ALDH) and cytochrome P450 2E1(CYP2E1), which all appear to be polymorphic.

体内参与乙醇代谢的酶主要有乙醇脱氢酶(ADH)、乙醛脱氢酶(ALDH)和细胞色素P450-2E1(CYP2E1)，它们均存在基因多态现象。

25. Pseudomonas cytochrome oxidase

假单胞菌属细胞色素氧化酶

26. Keywords Fatty liver;Cytochrome P4502E1;Immunohisochemistry;MDA;

关键词脂肪肝;细胞色素P4502E1;免疫组织化学;丙二醛;

27. Succinic dehydro-genase ( SDH) and cytochrome oxidase ( CCO) decreased slightly, and NADPHD disappeared after cold ischemia for 72 hours respectively.

冷藏72h后,琥珀酸脱氢酶(SDH)和细胞色素氧化酶(CCO)活性开始下降,NADPHD活性几乎完全丧失;

28. The mitochondrial cytochrome oxidase I(COI)gene sequence of larvae and adult of Cephenemyia trompe in reindeer for evolution by the molecular biology techniques.

利用分子生物学技术对驯鹿狂蝇蛆及其成蝇(Cephenemyia trompe)的线粒体COI基因种属特异性序列进行了研究。

29. Cytochrome P450-based gene therapy is a novel prodrug activation strategy for cancer treatment that has substantial potential for improving the safety and efficacy of cancer chemotherapies.

利用细胞色素P450治疗肿瘤是一种新的基因治疗方法,对提高肿瘤化疗的安全性和有效性有非常大的潜力。

30. A metal-free porphyrin, C32H32N4(COOH)2, that combines with iron to form the heme of hemoglobin, myoglobin, cytochrome, and other iron-containing proteins.

原卟啉一种不含金属的卟啉，C32H32N4（COOH）2，与铁结合形成血红蛋白、肌红蛋白、细胞色素和其它含铁蛋白质的血红素

31. Keywords reverse micelles;extraction;protein;cytochrome C;

反胶团;提取;蛋白质;细胞色素C;

32. Keywords Reverse micelle;Phase transfer;Cytochrome C;

反胶团;相转移;细胞色素C;

33. Keywords reverse micelles;extraction;cytochrome C;

反胶团;萃取;细胞色素C;

34. Besides, immunocytochemical staining indicated that EGCG downregulated the over-expression of cytochrome c in the cytosol induced by PQ.

另外,免疫细胞化学染色发现EGCG预处理可下调PQ诱导的细胞色素c在胞浆中的过表达。

35. phagocytespecific cytochrome

吞噬细胞特异性细胞色素

36. Azole and triazole drugs are cytochrome P450 inhibitors widely used as fungal antibiotics and possessing potent antimycobacterial actiity.

唑类和三氮唑类药物作为细胞色素P450抑制剂广泛被作为抗真菌药物和抗微生物药物使用。

37. A method for the cytochrome C-catalyzed fluorescence determination of artemisinin was developed using pyronine B(PB) as substrate.

在细胞色素C催化下,吡啰红B与青蒿素反应导致荧光降低,细胞色素C与青蒿素的反应为酶-底物模型。

38. In nature,the core of haemachrome,cytochrome,chlorophyl and other biological macromolecules are made up with porphyrin compounds that participate in a series of important process in the organism.

在自然界,卟啉化合物构成了血红蛋白、细胞色素及叶绿素等生物大分子的核心部分,参与生物体内一系列重要过程。

39. Effect of Compound Labiatae, Aspirin and Persantin on Cytochrome P-450

复方丹参片、阿斯匹林和潘生丁对细胞色素P-450的影响

40. Keywords PCBs;EROD;flounder;bioeffect;cytochrome P450;

多氯联苯;EROD;牙鲆;生物效应;细胞色素P450;

41. It is found in the enzyme cytochrome c oxidase, which is part of the respiratory electron-transport chain, and in the protein plastocyanin, which is involved in photosynthetic electron transport.

存在于细胞色素c氧化酶中，该酶是呼吸电子传递链上的一个部分。它还存在于质体蓝素蛋白中，和光合电子传递有关。

42. The results indicated that the lysine residues in cytochrome C molecules combine with cystine slowly.It induced the small conformational change of cytochrome C molecules.

实验结果表明，胱氨酸分子与细胞色素C的赖氨酸残基缓慢结合，二者相互作用的最终结果使细胞色素C分子的构象发生了微小的变化。

43. Study on the Cytochrome P450 Enzymes and CYP Genes in Thais Clavigera

对疣荔枝螺细胞色素P450酶系及其基因CYP的研究

44. A mixture of an aqueous dispersion of poly (ester sulfonic acid) or Eastman AQ38 (AQ) and a solution of cytochrome c (Cyt c) is cast on the surface of pyrolytic graphite (PG) electrodes, and Cyt c AQ films are formed after being dried.

将聚磺酸酯EastmanAQ38(AQ)与细胞色素c (Cytc)的混合水分散系涂布于热解石墨电极表面 ,晾干后可形成Cytc AQ薄膜 .

45. The DNA adduct formation and cytochrome P450 1A1 (CYP1A1) induction have been suggested to be the major determinant of their carcinogenic activity.

已知多环芳香烃对细胞色素P450 1A1 (CYP1A1) 之诱发能力和形成DNA键结物以及引起肿瘤形成呈正相关性。

46. Determination of cytochrome C was attempted with the aid of this salt bridge supported BLM system.

并对用该双层类脂膜体系电化学测定细胞色素C进行了初步尝试。

47. Study on Cytochrome Oxidase Isoenzymes by Introducing Laser Radiated DNA into Tomato[J].

引用该论文 邵耀椿,杨晓锋,丁海东,封国林.

48. The content of cytosolic malondialdehyde(MDA),the mitochondrial Ca2+ concentration([Ca2+]m)were detected and the content of cytosolic Cytochrome c(Cyt c)protein by Western blotting was evaluated.

心肌丙二醛(MDA)含量,心肌线粒体钙离子含量([Ca2+]m)、细胞质细胞色素C(Cytc)含量、细胞质caspase-3活性;

49. EHYP can induce the release of cytochrome C and the activation of caspase-3. Both L-NBP and VitE can ameliorate the release of cytochrome C and the activation of caspase-3.

慢性间断性缺氧能够诱导细胞色素C由线粒体至胞浆的释放和caspase-3 的激活。 维生素 E 和 L-NBP 能够降低细胞色素C的释放及 caspase-3 的裂解激活。

50. The CHL 3A4 cell line established did express human cytochrome P450 3A4 and could lead metabolic activation for three genotoxic chemicals AFB1, STC and CPA.

所建CHL?3A4细胞系确实能表达人细胞色素P4503A4，并能代谢活化AFB1、STC、CPA。

51. Aqueous two - phase extraction (ATPE) was applied in extraction of cytochrome C (Cyt c) from pork heart.

把化工上常用的双水相萃取法应用于生物分离,从猪心中纯化具有药用价值的细胞色素C。

52. Keywords anti-parasitic;cytochrome P450;liver microsome;

抗寄生虫;细胞色素P450;肝微粒体;

53. Antiretroviral agents have a propensity for causing drug interactions as a result of their ability to either inhibit or induce the cytochrome P450 (CYP) enzyme system.

抗逆转录病毒药物有可能引起药物相互作用，因为它们不是抑制就是诱导细胞色素酶P450（CYP）系统。

54. Abstract： OBJECTIVE To investigate the protective effects that phenobarbital sodium(Phe) induces cytochrome P450 (P450) against endotoxin (End).

摘 要： 目的 蜒究苯巴比妥钠诱导细胞色素P450(P450)对内毒素所致鼠毒性的保护作用。

55. Cytochrome P450 3A(CYP3A) is one of the key isoenzymes involved in the metabolism of clinical drugs.

摘要 细胞色素P450 3A（CYP3A）是参与临床药物代谢的主要CYP同工酶之一。

56. Aqueous two-phase extraction (ATPE) was applied in extraction of cytochrome C (Cyt c) from pork heart.

摘要把化工上常用的双水相萃取法应用于生物分离，从猪心中纯化具有药用价值的细胞色素C。

57. Objective To evaluate the diagnostic value of examining endometrial biopsy specimens for aromatase cytochrome P450 and CA125 for endometriosis.

摘要目的：探讨子宫内膜芳香化酶细胞色素P450（简称芳香化酶P450），CA125，联合检测对子宫内膜异位症（简称内异症）的诊断价值。

58. Methods Genomic DNA was isolated, and cytochrome c oxidase I (COI) and cytochrome b (Cyt b ) genes were amplified by polymerase chain reaction (PCR).

方法 实验室饲养的F1钉螺 ,单个抽提基因组DNA ,PCR扩增细胞色素c氧化酶I(COI)、细胞色素b(Cytb)基因并测序 ,用GENETYX MACver .

59. Methods: The expressions of Bel-XL , Bcl-2, cytochrome C and caspase-3 activity were studied by RT-CR and Western blot in the cisplatin-resistant (COC1/DDP) and cisplatin-sensitive human ovarian cancer cell line (COC1) .

方法:采用RT-PCR和Western Blot分析人卵巢癌顺铂敏感细胞株COC1和顺铂耐药株COC1/DDP中Bcl-XL、Bcl-2、细胞色素C的表达和caspase-3的活性。

60. Methods The serum level of ALT,liver index, contents of malondialdehyde (MDA) and glutathione (GSH),activity of microsomal cytochrome P450 and its isoform P4502E1 in liver were measured.

方法分别测定血清谷丙转氨酶(ALT)的活性,肝匀浆中谷胱甘肽(GSH)、丙二醛(MDA)的含量,肝微粒体中细胞色素P450及其亚型2E1的活性;

61. Methods The expression of aromatase cytochrome P450 in normal endometrium,endometrial hyperplasia and endometrial cancer were detected by immunohistochemical analysis.

方法应用免疫组织化学方法检测正常子宫内膜、子宫内膜增生症及子宫内膜癌中细胞色素芳香化酶P450的表达。

62. Methods Itraconazole is a inhibitor of the cytochrome P450(CYP)3A4 enzyme,which influence its substrate absorption and metabolism.

方法根据依曲康唑对CYP3A4的抑制作用,影响其底物药物吸收和代谢过程,探讨联合用药的药物相互作用。

63. Methods: Cytochrome C and lysozyme were selected as model samples ,and the some factors affecting electrophoretic separation were investigated, based on capillary zone electrophoresis(CZE) mode.

方法：采用高效毛细管电泳中自由区带电泳分离模式，以标准蛋白质细胞色素C与溶菌酶为分析对象，对影响电泳分离的因素进行了考察。

64. Cytochrome P450s of the insects play an important role in the insect resistance and detoxifcation metabolism.

昆虫细胞色素P450在昆虫抗药性、解毒代谢等方面具有重大研究价值。

65. A second problem with E. coli is the limited supply of complementary NADPH:cytochrome P450 reductase that is also essential for the correct function of reconstituted plant cytochrome P450 enzymes.

有关大肠杆菌的第二个问题是：限制补充NADPH，细胞色素P450还原酶对于再造植物细胞色素P450酶的正确功能所必须的。

66. The current advances of pharmacogenetics are discussed in this article,with an emphasis on the association between cytochrome P450(CYP2C19、CYP2D6、CYP1A1)gene polymorphisms and drug metabolisms.

本文介绍了药物遗传学的研究现状,并着重探讨三种细胞色素P450酶(CYP2C19、CYP2D6、CYP1A1)基因多态与药物代谢的关系。

67. This paper reports the purification of CCO from bovine heart with ammonium sulfate precipitation, phneyl - Sepharose CL-4B hydrophobic chromatographic and cytochrome C-Sepharose 4B affinity chromatographic methods.

本文应用硫酸铵分级沉淀、Phenyl-Sepharose CL-4B 疏水层析和 Cytocrome C-Sepharose 4B亲和层析的方法,从牛心肌中分离纯化了细胞色素C氧化酶。

68. The contributions of the cytochrome P450s to insecticide resistance were introduced,and the molecular mechanisms of P450-mediated insecticide resistance were analyzed in this article.

本文概述了昆虫细胞色素P450在昆虫抗药性中所起的作用及其目前的一些研究进展,从分子学角度分析了昆虫细胞色素P450介导昆虫抗药性的分子机制。

69. Many of the drugs used in angina pectoris are the substrate of cytochrome P450, drug interactions are easily to occur when antianginal drugs co-administrated with other drugs and foods.

本文综述了与常用抗心绞痛药物相关的药动学方面的相互作用研究进展,为临床用药提供参考。

70. The problems in study of Streptomyces Cytochrome P450, and the prospects for future study of cytochrome P450 and its application were also discussed.

本文综述了链霉菌中发现的细胞色素P450及其功能的研究进展,分析了存在的问题和研究应用前景。

71. In this study, MDS is adopted to simulate the structures of two kinds of metalloprotein, one is Metallothionein (MT), and the other is Cytochrome P450 (CYP).

本文采用该方法进行了两类含有金属离子的蛋白的结构模拟，其一是金属硫蛋白、其二是细胞色素 P450。

72. In this paper, we conducted the comparative study of the relationship among 38 passerines based on mitochondrial cytochrome b genes (Cytb) and nuclear adenylate kinase intron 5 (AK5) sequences.

本试验结合线粒体DNA细胞色素b(cytochrome b)和核腺苷酸激酶内含子5(Adenylate Kinase Intron 5)两个基因,采用DNA测序的方法研究了雀形目9科38种鸟类的系统发育关系。

73. Two cDNAs encoding cinnamate 4_hydroxylase homologues were isolated from Gossypium arboreum L. by PCR_mediated method using a primer based on a conserved region of plant cytochrome P450.

根据P450保守序列设计简并引物，从亚洲棉(Gossypium arboreum L.) cDNA文库中分离到两个肉桂酸_4_羟化酶(C4H)同源cDNA克隆。

74. Keywords plant;cytochrome P450;gene clone;xenobiotics;

植物;细胞色素P450;基因克隆;外来物质;

75. Keywords OGP;spermicide;mitochondria sheath;cytochrome C oxidase;

正辛基-葡萄糖苷（OGP）;体外杀精;线粒体鞘;细胞色素C氧化酶;

76. The oxidized absorption spectra of cytochrome b-563 had peaks at 420, 535 nm and the reduced form had major peaks at 430, 533, 563nm.

氧化型细胞色素b-563的吸收峰为420、535毫微米,还原型为430、533、563毫微米。

77. The activity of succinic dehydrogenase (SDH),cytochrome C oxidase(CCO)were assayed.

测定 3组细胞线粒体的琥珀酸脱氢酶 (SDH)比活力、细胞色素C氧化酶 (CCO)比活力 ;

78. The Bradford method was used to measure the concentration of protein in liver microsome, and activities of cytochrome P450 enzymes were determined by the spectrophotometer method.

测定一月龄至八月龄不同性别的猪，肝微粒体蛋白含量、CYP450含量、CYPb5含量、NADPH-细胞色素C还原酶活性、氨基比林-N-脱甲基酶活性、红霉素-N-脱甲基酶活性和苯胺-4-羟化酶活性。

79. The antiseptic effects of preservatives in compound cytochrome C eye drops on escherichia coli,staphylococcus aureus,pseudomonas aeruginosa,candida albicans and aspergillus niger were tested.

测定复方细胞色素C滴眼液中防腐剂对大肠杆菌、金黄色葡萄球菌、铜绿假单胞菌,白色念珠菌和黑曲霉的抑菌作用。

80. Pathological Changs of liver, serum levels of TC, TG, ALT, AST, FFA, SOD, MDA, liver levels of TC, TG, FFA, SOD, MDA and the expression of hepatocyte cytochrome P450II El were observed.

测定血中甘油三酯(TG)、总胆固醇(TC)、谷丙转氨酶(ALT)、谷草转氨酶(AST)、游离脂肪酸(FFA)、超氧化物歧化酶(SOD)、丙二醛(MDA)； 测定肝组织匀浆中TC、TG、FFA、SOD、MDA；