dystrophy

dystrophy

1. Human LMO7, a nuclear membrane protein, has been shown to function as a transcription factor that can control expression of Emery-Dreifuss muscular dystrophy (EDMD) related genes.

a在人类细胞中，LIM domain only 7 (LMO7) 属于一个核内蛋白质，同时具有往来于细胞核及细胞质的能力，也具有调控Emery-Dreifuss muscular dystrophy (EDMD) 此疾病相关基因表达的能力。

2. Nowadays,BIGH3 gene mutation related corneal dystrophy is the most common etiological factor leading to corneal dystrophy in genetics.

BIGH3基因突变有关的角膜营养不良现今已是角膜营养不良最常见的遗传学致病因素。

3. The muscle cell tropism of CVB 1 provides experimental basis for constructing new vector targeting to muscle cells in gene therapy of Duchenne muscular dystrophy.

CVB1 的嗜肌肉特性为在DMD等肌萎缩症的基因治疗中探索靶向载体提供了实验依据

4. The pathophysiology of dko mouse was very similar to Duchenne muscular dystrophy (DMD), and dko mouse is an ideal animal model for study of DMD clinical therapy.

dko小鼠的病理生理学表现与DMD极为相像,是DMD临床治疗研究的理想疾病动物模型。

5. Duchenne muscular dystrophy (DMD): A quantitative study of type 2C fibers and muscle satellite cells.

Duchenne型肌营养不良症:2c型纤维与肌卫星细胞的定量研究

6. The abnormal distribution and significance of lectin receptors in skeletal muscle of the patients with duchenne mys-cular dystrophy (DMD).

Duchenne型肌营养不良症骨骼肌凝集素受体异常分布及其意义

7. Australian Neuromuscular Research Institute (ANRI) executive officer Brett Tizard says the group has designed a "genetic band-aid" to repair the muscle protein that causes Duchenne muscular dystrophy.

一个来自澳大利亚珀斯的研究小组说：他们找到了迄今为止最有希望成功治疗致病进行性肌营养不良的方法。

8. Clinical for muscular dystrophy, myasthenia gravis, muscular dystrophy, polymyositis, motor neuron disease, such as atrophy disease syringomyelia.

临床用于肌肉萎缩、重症肌无力、肌营养不良、肌炎、运动神经元病、脊髓空洞症等痿症。

9. Human cone-rod dystrophy sufferers are sighted at birth, but lose first their central colour vision in early adulthood, before slowly losing their peripheral black and white vision as well.

人类遗传性锥体杆体营养不良患者出生时视觉正常，但成年早期即丧失中央性色觉，进而逐渐丧失外周性黑白视觉。

10. What is neuromuscular disease and muscular dystrophy?

什么是神经肌肉疾病和肌肉萎缩症?

11. Emery-Dreifuss muscular dystrophy is a condition that chiefly affects muscles used for movement (skeletal muscles) and heart (cardiac) muscle.

什麽是'埃默里-德赖富斯营养不良-遗传性疾病骨骼肌和心脏'?

12. He thought Lora distinctive and agreed with him donation some of the dividend to the dystrophy dweller nearby as the duration drought.

他以为劳拉是与众不同的并且能够同意他把红利的一部分捐赠给附近因为持续的干旱而营养不良的居民。

13. He had muscular dystrophy.

他患了肌肉萎缩症。

14. But despite the good intentions, choosing to run away from it is literally putting yourself on dystrophy mode.

但是除去这些好的意愿，你选择逃避才是真正使你心情不好的原因。

15. Dystrophin, the protein missing in Duchenne muscular dystrophy patients, conducts this energy across the muscle cell's membrane, protecting the fiber.

但肌节产生的力量，如果没有向外引导的话，也会伤害肌纤维，DMD患者所缺乏的肌肉萎缩蛋白，能将这股力量传导到肌肉细胞膜上，而保护肌纤维。

16. The SK3 channel was overexpressed in skeletal muscles after denervation and in patients with myotonic dystrophy(DM).

使去神经支配和肌强直营养不良患者骨骼肌SK3表达显著上调。

17. Diseases like multiple sclerosis, muscular dystrophy or polio can leave people disabled.

像多发性硬化症、肌肉萎缩症或小儿麻痹症等疾病会使人残疾。

18. Dyskeratosis congenita （DC） is a rare inherited disorder characterized by the triad of heterochromia-like pigmentation, nail dystrophy and mucosal leucoplakia in the mouth or vagina.

先天性角化不良是一种少见的先天遗传性皮肤病，其临床三联征包括：甲板营养不良，口腔或阴道等可出现白斑，皮肤异色症样的色素沉着。

19. Dyskeratosis congenita (DKC) is a rare inherited disease characterized by the triad of abnormal skin pigmentation, nail dystrophy, and mucosal leukoplakia.

先天性角化不良症（DKC）为一少见之遗传性疾病，三项主要特徵为皮肤色素异常、 指甲生长异常及黏膜白斑症。

20. The proband was a 9-year-old boy, with reticular pigmentation of the skin, leukoplakia in the oral mucosa, dystrophy of all nails and disproportionate dentition.

先证者男,9岁。全身呈网状棕黑色色素沉着,口腔黏膜白斑,牙齿排列不整齐,20甲营养不良。

21. And millions of people around the world suffer from other incurable diseases such as cystic fi brosis multiple sclerosis muscular dystrophy and genetic birth defects.

全世界数以百万计的人们遭受其它一些不可治愈的疾病，比如囊肿型纤维化、多发性硬化症、肌营养不良症和遗传性出生缺陷。

22. Other eye conditions can cause corneal ulcers, such as entropion, distichia, corneal dystrophy, and keratoconjunctivitis sicca.

其他疾病也能引起角膜溃疡，例如眼睑内翻、双行睫毛、角膜营养不良和角膜干燥。

23. The Muscular Dystrophy Association of Canada provides relevant and current information about many types of neuromuscular disorders in an easy to understand format.

加拿大肌肉萎缩协会提供相关且当前有关于许多类的神经肌肉疾病资讯，以简单的方式来帮助了解。

24. Following symptoms: rest pain and tissue necrosis, ischemic neuropathy, skin color changes, skin adnexal dystrophy, disuse muscle atrophy and joint stiffness etc.

发展后可出现静息痛及组织坏疽、缺血性神经病变、皮肤色泽改变、皮肤附属器营养障碍、废用性肌萎缩及关节僵硬等症状。

25. A disorder due to a similar molecular basis, myotonic dystrophy 1 (DM1), is known to have white matter hyperintensities on cranial MRI.

另一种有类似分子病理学基础的疾病：萎缩性肌强直(DM1)患者的核磁共振成像也有白质高信号。

26. For people with Cerebral Palsy and Muscular Dystrophy only. Participants who need personal care should attend with an assistant.

只供较严重之痉挛或肌萎人士。如参加者需要个人照顾，需有家人或朋友陪同出席。

27. He is the first of four patients with spinal cord(6) injuries, muscular dystrophy(7), stroke or motor neurone(8) disease testing the brain-to-movement system developed in Massachusetts.

四个分别患有脊髓损伤，肌肉失调，中风和运动神经元疾病的病人参与测试了这个在马萨诸塞州研制成功的大脑支配行动的装置。雷是他们中的第一个。

28. According to this study, the anticancer drug trichostatin A or TSA increases muscles fiber size in two mouse models of muscular dystrophy.

在两个类型老鼠上，每日TSA射入增加了肌纤维大小并且减少了肌肉的纤维化(结疤)和发炎的症状。

29. Inherited gene mutations, such as those that cause hemophilia or muscular dystrophy, would have to be corrected as well before using a patient's own cells to create ES cells.

在使用带有遗传性基因突变（例如血友病或肌肉营养性萎缩症）患者的细胞来制造胚胎干细胞之前，也需要先矫正缺陷基因。

30. First of all, mutation analysis of Duchenne muscular dystrophy (DMD) gene was carried out by CE coupled with multi-PCR technique.

在医学领域主要表现为以基因突变检测，基因家系连锁分析，特定基因的PCR产物直接检测为基础的基因诊断。

31. The department also develops and applies the up-to-date new treatment for the diseases which cannot be effectively treat before, such as motor neuron disease, intractable epilepsy, stroke, dementia, and muscular dystrophy.

在治疗上引进最新的疗法与欧美新开发药物以治疗在过去无法医治的神经疾病，包括各种不随意运动症，癫痫症、脑中风、失智症及肌萎缩症之治疗。

32. Complex regional pain syndrome(CRPS),previously known as reflex sympathetic dystrophy(RSD),is not well recognized yet among physicions at present.

复杂性区域疼痛综合征,目前尚不大为医师们所熟悉。

33. Approximately one in every 3,500 boys worldwide is afflicted with Duchenne muscular dystrophy with 20,000 new cases reported each year.

大约每3500男孩全世界患有杜氏肌营养不良的20000新病例每年报告。

34. She can't eat and become dystrophy.

她无法进食而变得营养不良。

35. She was the poster child for muscular dystrophy.

她是海报上那个患肌肉萎缩的小孩。

36. M.J. Willard: We have a number of people who have mobility impairments such as spinal cord injuries, Multiple Sclerosis, Muscular dystrophy.

威拉德：我们国家有很多患有像脊髓受伤、多发性硬化、肌肉萎缩症引起的运动障碍等病症的残疾人。

37. It will bring cures a step closer for Alzheimer's and Parkinson's disease, diabetes, muscular dystrophy and heart disease.

它将进一步促进对阿尔滋海默症，帕金森症，糖尿病，肌肉萎缩症和心脏病等疾病的治疗。

38. As for your friend's children, they have a mutation causing their Duchenne muscular dystrophy that will not be helped by the drug we are currently trialling.

对于你朋友的孩子，有个基因导致杜氏抗肌萎缩蛋白缺失，而目前的治疗并不能对这个基因有所作用。

39. Appropriate nutrition evaluation and support for stroke patients with dystrophy may help reduce complications and improve the outcome.

对脑卒中后可能出现营养障碍的患者进行营养评估及营养支持,会减少并发症,改善预后。

40. This year I was chosen to be the Maryland State Goodwill Ambassador for the Muscular Dystrophy Association.

小马蒂的诗和他的经历引起美国媒体的关注，不少新闻机构都曾在节目中采访过他。

41. Just a week later, another group reported making patient-specific iPS cell lines for 10 different diseases, among them muscular dystrophy, type 1 diabetes, and Down syndrome.

就在一周后，另一组报告生成了10种不同的疾病的患者特异性的多能性干细胞系，其中包括肌肉萎缩症、I型糖尿病和唐氏综合症。

42. Intramembrane proteinic particles of muscle plasma membrane were calculated with freeze-fracture electron microscopy in 4 cases of Duchenne muscle dystrophy (DMD) .

应用冷冻断裂电镜技术对Duchenne型肌营养不良症(DMD)的骨胳肌标本4例(异常组),正常标本2例(正常组)肌细胞质膜的蛋白颗粒进行电镜观察。

43. Intramembrane protein particles of erythrocyte plasma membrane were calculated with freeze frecture electron microscopy in 5 cases of Duchenne muscular dystrophy (DMD).

应用冷冻断裂电镜技术，对5例Duchenne型肌营养不良症（DMD）的血液标本（DMD组）和3例正常标本（对照组）红细胞质膜的蛋白颗粒进行观察。

44. Detection deleted Duchenne muscular dystrophy carriers by fluorescence quantitative polymerase chain reaction.

应用荧光定量PCR检测缺失型DMD携带者的研究

45. Myotonic dystrophy is a degenerative disease characterized by progressive muscle wasting and weakness.

强直性肌营养不良是一种退行性疾病，以进展性肌肉萎缩和无力为特征。

46. Patients with myotonic dystrophy, the most common form of adult-onset muscular dystrophy, have a high prevalence of insulin resistance due to disruption of the insulin receptor.

强直性肌营养不良是最常见的成年发病的肌营养不良症，由于胰岛素受体的破坏导致胰岛素抵抗的发病率很高。

47. People with myotonic dystrophy have prolonged muscle tensing （myotonia） and are not able to relax certain muscles after use.

强直性肌营养不良病患具长期肌肉拉紧（肌强直）和在使用后无法放松某些肌肉。

48. Harley-Davidson and the Muscular Dystrophy Association (MDA) mark the 25th anniversary of their partnership.

当年是哈雷戴维森支持肌肉萎缩症协会(MDA)的第25个年头。

49. Quick movements cause muscle stiffening.There is also a myotonic form of muscular dystrophy.

快速运动会引起肌强直，肌营养不良是另一种肌强直类型。

50. People with myotonic dystrophy have prolonged muscle tensing (myotonia) and are not able to relax certain muscles after use.

患有强直性肌营养不良者骨骼肌收缩为持续性收缩（强直），特定肌肉在使用后不能放松。

51. Muscular dystrophy sufferer Lee Kai-leung, 18, has no intention of resting on his laurels (25 points in six best subjects in HKCEE), but has vowed to study even harder.

患肌肉萎缩症的李启亮，现年十八岁，并不满足既有的成绩(会考最好六科25分)而不思进取，他誓加倍努力。

52. A congenital condition caused by a deficiency of thyroid hormone during prenatal development and characterized in childhood by dwarfed stature, mental retardation, dystrophy of the bones, and a low basal metabolism.

愚侏儒病一种因在胎儿发育期间缺乏甲状腺激素导致的先天性病症，症状为在少儿时期体型矮

53. A congenital condition caused by a deficiency of thyroid hormone during prenatal development and characterized in childhood by dwarfed stature,mental retardation,dystrophy of the bones,and a low basal metabolism.

愚侏儒病一种因在胎儿发育期间缺乏甲状腺激素导致的先天性病症，症状为在少儿时期体型矮小、智力迟钝、骨骼营养不良以及基本的新陈代谢能力低下

54. Abstract: Objective To investigate the apoptosis of skeletal muscles in mdx mice,and study the effect of apoptosis on the pathogenesis in Duchenne muscular dystrophy (DMD).

摘 要：目的 研究mdx鼠体内骨骼肌细胞凋亡情况，探讨凋亡对 Duchenne型肌营养不良症（DMD）的发生发展所起的作用。

55. Progressive muscular dystrophy is a group of inherited disorders characterized by progressive skeletal muscle wasting and weakness, which was not of neurogenic origin.

摘要 进行性肌营养不良是一组以进行性骨骼肌萎缩和无力为特征的肌源性肌病。

56. A patient with traumatic rotator cuff tear of right shoulder developed severe myofascial pain syndrome with reflex sympathetic dystrophy (RSD) involving the right upper extremity.

摘要一位右肩遭受创伤性旋转环带撕裂伤的患者，在其右侧上肢发展出严重的肌筋膜疼痛症候群、合并有反射性交感神经失养症。

57. Reflex sympathetic dystrophy (RSD) has appeared in the literature under a confusing array of designations and confronted physicians since its original description in 1864.

摘要反射性交感神经失养症(RSD)自1864年首次被描述后，即以不同的定义与名称出现在文献上。

58. We report a laboratory-confirmed pediatric case of congenital myotonic dystrophy (CMD) in Taiwan.

摘要我们报告一例台湾地区之先天型肌强直失状症的儿童个案。

59. Objective To summarize the clinical characteristics of myotonic dystrophy (DM).

摘要目的总结强直性肌营养不良症(DM)的临床特点。

60. Objective To study the clinical and pathology features of myotonic dystrophy (DM).

摘要目的探讨强直性肌营养不良症(DM)的临床及肌肉病理学的特点。

61. Gelatinous drop-like corneal dystrophy (GDLD) is an autosomal recessive hereditary disease, which may result in bilateral loss of vision.

摘要胶滴状角膜营养不良是一种罕见的常染色体隐性遗传病，可导致视力严重障碍甚至失明。

62. In fleck corneal dystrophy,the lesion only involved stroma,epithelium and endothelium levels were normal.

斑点状角膜营养不良病变仅累及基质层,而角膜上皮层及内皮层正常;

63. Results Seven individuals with central areolar macular dystrophy were demonstrated in the family in 3 continuous generations, affecting both males and females.

早期患者视力正常，黄斑区轻度色素变动，随病情进展出现黄斑萎缩。

64. Individuals with Duchenne muscular dystrophy usually lack dystrophin completely while thosewith Becker muscular dystrophy have dystrophinof an altered size.

是最常见的一类进行性肌营养不良症。

65. The first myostatin-blocking drugs to have been developed are antibodies against myostatin, one of which may soon undergo clinical testing in muscular dystrophy patients.

最先开发成功的肌肉生长抑制素的阻断剂，是肌肉生长抑制素的专一性抗体，其中一种很快将进行临床试验，治疗DMD患者。

66. Some types of Muscular Dystrophy can affect the heart, causing cardiomyopathy or arrhythmias .

有些种类的肌肉萎缩症会影响心脏，导致心肌病或心律失常 。

67. Duchenne muscular dystrophy(DMD) takes up 75%(12 cases) in 16 PMD cases,which slightly higher than reference reported.

本组16例PMD中DMD占75%(12/16),比文献报道稍高[2];

68. Duchenne muscular dystrophy, in which muscle degeneration can cause a person's heart and diaphragm to fail, is one of the most prevalent.

杜兴肌营养不良是最常见的肌病之一，它导致的肌肉退化能使人的心脏和横膈膜功能丧失。）

69. Duchenne Muscular Dystrophy (DMD) is one of the most common fatal genetic disorders to affect children around the world.

杜氏肌营养不良（DMD）是最常见的致命的遗传疾病之一，影响到世界各地的儿童。

70. Based on her clinical presentation, reflex sympathetic dystrophy (RSD) was diagnosed.

根据临床症状，诊断为反射性交感神经失养症。

71. Qi Long Lu and researchers from the Hammersmith Hospital in London treated more than 30 mice with a form of muscular dystrophy.

此前的研究发现，杜氏肌营养不良症是人体内的一个基因产生缺陷所致。

72. In addition, the charities Muscular Dystrophy Campaign (MDC), Action Duchenne and Duchenne Family Support Group also participate in the Consortium.

此外，肌肉萎缩症慈善运动（MDC），行动和裘馨裘馨家庭支援组也参加了联盟。

73. Boccia is suitable for the people with cerebral palsy and muscular dystrophy to play.

此活动特别为严重痉挛及肌肉萎缩人士参与。

74. Wellstone Cooperative Muscular Dystrophy Research Center at the university, one of three MD “centers of excellence” co-funded by the National Institutes of Health and MDA.

此研究结果刊登在今天的自然医学在线版上，结果还将刊登在8月份的出版的自然医学杂志上。

75. Couples can offer sex selection to couples if there is a risk of a gender-linked genetic condition, such as haemophilia, muscular dystrophy or colour blindness.

比如,当某种遗传性疾病同婴儿性别有关时，处于回避疾病的目的，可以对婴儿的性别进行选择。

76. The clinical review of 64 woman dystrophy of vulva who treated with guishao shouwu zuoguiyin.

用归芍首乌左归饮加减治疗外阴营养不良64例。

77. The diseases, included primary and secondarary renal diseases, acyesis, muscular dystrophy, and cancer and also were examed with the electron microscopy.

病种包括原发性和继发性肾脏疾病、肌营养不良、男性不育症和肿瘤。

78. Leukemia, cancer, aplastic anemia, thalassemia, muscular dystrophy, there are other diseases such as glaucoma patients, can also be used over the same treatment modalities.

白血病、癌症、再生障碍性贫血、地中海贫血、进行性肌营养不良，还有青光眼等其他病症的患者，同样也可以采用以上救治方式。

79. Objective To establish a simple and reliable method to examine the detection of dystrophin gene in patients and carriers with Duchenne muscular dystrophy (DMD) to lay a foundation for prenatal diagnosis.

目的 建立一种简便、可靠的缺失型Duchenne型肌营养不良(DMD)患儿及携带者的基因检测方法,为DMD产前诊断的开展奠定基础。

80. Objective To set up a fluorescent in situ hybridization(FISH) based method to detect the gene-deleted female carriers of Duchenne/Becker muscular dystrophy (DMD/BMD).

目的 建立应用荧光原位杂交 (fluorescent in situ hybridization,FISH)方法检查进行性假肥大性肌营养不良 (Duchenne/ Becker muscular dystrophy,DMD/ BMD)患者家系中女性亲属是否为携带者的方法。