hyperalgesia

hyperalgesia

1. The rats developed hyperalgesia after CCI and IT SB203580 administration significantly increased MWT in a dose dependent manner.

CCI后大鼠产生了机械痛敏,鞘内注射SB203580剂量依赖性地提高了MWT。

2. Expression of NGF amd BDNF in the Dorsal Root Ganglion and the Spinal Dorsal Horn in the Rat Following Peripheral Inflammatory Hyperalgesia

NGF和BDNF在炎性痛大鼠背根神经节和脊髓角的表达

3. The NR2B antagonists have shown the potential in neuronal protection and prophylaxis of hyperalgesia, drug-dependence and Parkinson's diseases in rodent models.

NR2B亚型阻滞剂在神经元保护、镇痛、抗药物依赖、抗帕金森病等方面表现了潜力。

4. auditory hyperalgesia

[医] 听觉性痛觉过敏

5. zones of hyperalgesia

[医] 痛觉过敏带, 海德氏带

6. On the one hand, after nerve compression, the afferent neurons increase the release of substance P, Glutanic acid and other pain transmitters, which will induce hyperalgesia.

一方面,外周神经压迫损伤后,初级传入神经元释放的P物质,谷氨酸等疼痛介质增加,诱发痛觉过敏。

7. An animal model of masticatory muscle hyperalgesia induced by experimental individual molar movement in rats

个别后牙移动导致大鼠咀嚼肌痛觉敏感模型的建立

8. In clinic, pathological pain is one of the most frequently observed clinical symptoms, which is characterized by a persistent spontaneous pain, hyperalgesia and touch-evoked pain (allodynia).

临床病理性痛可表现为持续性的自发痛及伴有长时程持续性痛敏和触诱发痛现象。

9. To avoid the development of anticipatory pain and hyperalgesia, the investigators recommend closer attention to pain management for neonates.

为避免出现预期疼痛和对疼痛过敏,研究人员推荐对新生儿的疼痛处理要更加密切关注。

10. Keywords sympathetic efferent;hyperalgesia;adrenoceptor;unitary discharge;diabetes;rat;

交感传出;痛过敏;肾上腺素能受体;单位放电;糖尿病;大鼠;

11. Location of spared nerve injury-induced central hyperalgesia and its action way

保留神经损伤诱致中枢痛敏的发生部位及其作用方式的实验观察

12. Keywords 5-HT2A receptor;Formalin;Inflammatory hyperalgesia;Spinal cord;Nitric oxide synthase;Endogenous opioid analgesia;

关键词5-HT2A受体;福尔马林;炎性痛觉过敏;脊髓;一氧化氮合酶;内源性阿片镇痛;

13. Keywords CFA;astrocytes;group III mGluRs;long-term hyperalgesia;

关键词CFA星形胶质细胞;第III组代谢型谷氨酸受体;长时程热痛敏;

14. Keywords pain;hyperalgesia;spinal cord;receptor;N-methyl-D-aspartate;dynorphin;rat

关键词疼痛;痛觉过敏;脊髓;受体;N-甲基-D-天冬氨酸;强啡肽;大鼠;

15. Keywords Dorsal root ganglia;Dorsal horn of spinal cord;Hyperalgesia;NMDAr;Non-NMDAr;

关键词脊神经节;脊髓背角;痛觉过敏;N-甲基-D-天门冬氨酸受体;非-N-甲基-D-天门冬氨酸受体;

16. Keywords herniation of lumbar intervertebral disc;nucleus pulposus;hyperalgesia;animal model;

关键词腰椎间盘突出;痛觉过敏;动物模型;

17. Keywords autologous nucleus pulposus;hyperalgesia;sciatica;

关键词自体髓核;痛觉过敏;坐骨神经痛;

18. Keywords Nucleus pulposus;Hyperalgesia;Dorsal root ganglion;Glial cell line-derived neurotrophic factor;

关键词髓核组织;痛觉过敏;背根节;胶质细胞源性神经营养因子;

19. Visceral hyperalgesia

内脏痛觉过敏

20. Visceral hyperalgesia and it's central sensitization

内脏痛觉过敏及其中枢敏感化

21. Chemical lumbar sympathectomies were performed on coloproctitis hyperalgesia model and colon-rectum distension (CRD) was used as harm disturbing.

利用直、结肠慢性刺激性炎性致痛模型,切除模型大鼠的腰交感神经后,运用机械扩张刺激观察大鼠行为变化。

22. Coloproctitis hyperalgesia and colon-rectum distension (CRD) can be smoothed by chemical lumbar sympathectomy in central nervous system(P<0.05).

化学性腰交感神经切除术CLS无论作为预防性手术还是治疗性手术均能使中枢内GFAP和COX2表达阳性的细胞数下降(p<0.05)。

23. Behavioral assessment of masseter mechanical hyperalgesia in rats with unilateral malocclusion

单侧咬合创伤致大鼠咬肌痛觉敏感的行为学研究

24. Only rats in the NP group showed eidence of irreersible mechanical hyperalgesia after surgery.

只有在髓核组在术后出现不可逆性痛觉过敏。

25. Related neural mechanisms between visceral hyperalgesia and morphine tolerance

吗啡耐受及内脏痛敏的相关机理

26. hyperalgesia, auditory

听觉性痛觉过敏

27. Peripheral tissue and nerve injury lead to chronic pain symptoms, including spontaneous pain, allodynia and hyperalgesia.

周围组织和神经受到损伤引起自发性疼痛、触刺激诱发痛和痛觉过敏等慢性痛症状。

28. Keywords Occlusion trauma;Tooth movement;Masseter muscle;Hyperalgesia;

咬合创伤;牙齿移动;咬肌;痛觉敏感;

29. Many researchers, therefore, have amelioration of hyperalgesia and allodynia foremost in their minds as they hunt for new analgesics.

因此,许多研究人员在寻求新的止痛药方时,都会把解除痛觉过敏及异位疼痛列入优先考量。

30. Acute hyperalgesia is detected at the remaining part of the tail as well as hindpaw.

在截尾5周后,小鼠后肢和余下的尾端出现痛敏反应。

31. In this thesis, a systematic study of hyperalgesia induced by different inflammatory agents was conducted, and the results were compared between wild-type mice and ASIC3 knockouts.

在此,我将对于不同药物所引发的发炎反应以及伴随而来的疼痛过敏化现象作一有系统的研究,比较野生型和ASIC3剔除小鼠的差异来推论ASIC3所扮演的角色。

32. Keywords nociceptin;bee venom test;persistent spontaneous pain;hyperalgesia;inflammation;anti-nociception;anti-inflammation;

孤啡肽;蜜蜂毒试验;持续性自发痛;痛敏;炎症;抗伤害作用;抗炎作用;

33. Chronic visceral hyperalgesia

慢性内脏痛敏

34. Inflammation and trauma lead to enhanced pain sensitivity (hyperalgesia), which is in part due to altered sensory processing in the spinal cord.

报道:炎症和创伤能增加一个人对疼痛的敏感性,部分地因为发炎能改变脊髓如何处理疼痛感。

35. Abstract : Nerve injury produces a long lasting neuropathic pain, manifested as allodynia, a decrease in pain threshold and hyperalgesia, an increase in response to noxious stimuli.

摘 要 :神经损伤可产生神经病性疼痛, 表现为持续性痛超敏和痛觉过敏。

36. A case with trauma history suffered from hyperalgesia, swelling and stiffness over bilateral upper extremities, numerous medications treatments were unsuccessful.

摘要此病例在创伤后双侧上肢遭受痛觉过度敏感、肿胀与僵硬,多种药物治疗效果不彰。

37. Methods:SD rat CCI (chronic constriction injury) hyperalgesia model was used as the neuropathic pain model, and hyperalgesia score employed as the sign of neuropathic pain.

方法:采用轻微结扎一侧大鼠坐骨神经的神经痛模型,以光热辐射引起的大鼠双下肢抬脚潜伏期的差值作为神经痛的指标(痛敏分数)。

38. The Sunburn Pain Model: The Stability of Primary and Secondary Hyperalgesia Over 10 Hours in a Crossover Setting Burkhard Gustorff, Sebastian Anzenhofer, Thomas Sycha, Stephan Lehr, and Hans G. Kress

晒伤痛模型:在一个交叉装置上原发和继发性痛觉过敏10小时以上的稳定性

39. Rossel P.Drewes AM.Petersen P.Nielsen J, ArendtNielsen L Pain produced by electric stimulation of therectum in patients with irritable bowel syndrome: further evidence of visceral hyperalgesia 1999

李延青.王艳梅.吕国苹.顾晓萌.左秀丽.张海燕直肠内温度变化影响肠易激综合征患者内脏感觉阈值[期刊论文]-胃肠病学2003(11

40. Keywords Duzhongyaotong pill;non-compressive nucleus pulposus protrusion;hyperalgesia;nerve root;

杜仲腰痛丸;非压迫性髓核突出;痛觉过敏;神经根;

41. Keywords Inflammatory pain and hyperalgesia;Nitric oxide synthase;Nitric oxide synthase inhibitors;Nociceptive threshold;Aminoguanidine;Hot-plate test;

炎性痛及痛过敏;一氧化氮合酶;一氧化氮合酶抑制剂;痛阈;氨基胍;热板;

42. Inflammatory hyperalgesia

炎性痛觉过敏

43. thermal hyperalgesia

热痛觉过敏

44. Keywords Heat pain threshold;Nitric oxide;Hyperalgesia;

热痛阈;一氧化氮;痛觉过敏;

45. The relieving effect of cyclooxygenase inhibitors and prostaglandin receptor blocker on hyperalgesia of diabetic rats

环加氧酶抑制剂和前列腺素受体阻断剂缓解糖尿病大鼠的痛过敏

46. The effect of microglia and its related molecule on signal transduction of hyperalgesia will be reviewed in this article.

现就总结近年来小胶质细胞及其相关分子在痛敏信号转导中作用的研究进展。

47. hyperalgesia, hyperalgia

痛觉过敏

48. Hyperalgesia (the lowering of pain threshold and an exaggerated response to a painful stimulus);

痛觉过敏(痛阈下降和对正常情况下的疼痛刺激的反应性增加);

49. Keywords Hyperalgesia;Allodynia;P2X3 receptor;Trigeminal ganglion;

痛觉过敏;触诱发痛;P2X3受体;三叉神经节;

50. Hyperalgesia: increased response to noxious stimulation.

痛觉过敏。对正常的疼痛刺激有增强的反应。

51. zone of hyperalgesia

痛觉过敏区

52. Keywords hyperalgesia;prostaglandin;unitary discharge;diabetes;rat;

痛过敏;前列腺素;单位放电;糖尿病;大鼠;

53. Keywords Somatosensary evoked potentials;Nucleus pulposus;Nerve root injury;Hyperalgesia;

皮层躯体感觉诱发电位;髓核;神经根损伤;痛觉过敏;

54. There are many hypothesis mainly concentrated in peripheral and central hyperalgesia mechanism as well as psychology element.At present,some peptides and medium has been paid attention to.

目前研究主要集中于几种相关肽和介质,并且作用于相关神经递质的选择性药物已经获得,但要广泛应用于临床治疗还需要进一步的研究。

55. Objective:To observe the effect of single electroacupuncture (EA) treatment and multiple EA treatment on hyperalgesia score of neuropathic pain in the rat.

目的:从单次电针实验和多次电针实验两方面,观察电针对神经痛大鼠痛敏分数的影响。

56. Aim:Formalin test was used to examine the role of Chlorpromazine in hyperalgesia induced by tissue injury.

目的:用福尔马林致炎模型研究蛋白激酶C(PKC)非特异性抑制剂氯丙嗪在组织损伤所致痛觉过敏中的作用。

57. Objective: By giving mechanical and chemical stimuli to adult rats, our aim was to investiqate the mechanism of visceral hyperalgesia.

目的:通过对成年大鼠给予机械和化学伤害性刺激,探讨内脏痛觉过敏产生的机制。

58. Objective To observe the injuries to the dorsal root ganglion(DRG) derived by auto transplantation of nucleus pulposus and find out the relationship between the injuries and the hyperalgesia.

目的观测髓核组织对背根节(DRG)的损伤作用,探讨这种损伤作用与痛觉过敏之间的关系。

59. Changes of NOS activity in dorsal horn of spinal cord during formalin induced inflammatory pain and hyperalgesia in rats

福尔马林炎症痛诱导的大鼠脊髓后角一氧化氮合酶的变化

60. Results:Edaravone can reduce the mechanical hyperalgesia induced by spinal nerve ligation.

结果:依达拉奉可以减轻脊神经结扎引起的痛敏现象;

61. RESULTS: Transection of the tibial and sural nerves induced cold allodynia and moderate mechanical hyperalgesia.

结果:胫神经和腓肠神经的横断导致异常性冷疼痛和中等强度的机械性痛觉过敏。

62. Conclusion NO is involved in nociceptive transmission at the spinal cord following nerve injury and it may result in hyperalgesia and allodynia.

结论NO参与神经损伤后脊髓后角内痛觉调制,提示NO在痛觉过敏、异常疼痛产生机制中发挥重要作用。

63. In summary, among the factors accounted for hyperalgesia or hypoalgesia, the extent of nerve injury always plays a key role.However, there hadn’t been a direct animal study about this.

综上所述,在导致神经压迫后不同感觉变化的各种原因中,神经损伤程度都起到了关键作用,但是目前还没有关于这两者关系的实验动物研究。

64. Keywords elderly rat;persistent spontaneous pain;mechanical hyperalgesia;heat hyperalgesia;bee venom test;formalin test;

老龄大鼠;持续性自发痛;机械性痛敏;热痛敏;蜜蜂毒试验;甲醛试验;

65. On the other hand, the injured nerve also produces ectopic discharge, gives rise to the peripheral and central sensitization and induces hyperalgesia.

而另一方面,神经损伤后可产生异位放电,促使外周和中枢敏化,导致痛觉过敏的产生。

66. Keywords botulinum toxin type A(Btx-A);mechanical allodynia;thermal hyperalgesia;peritoneal injection;neuropathic pain;rat;

肉毒毒素A;机械性触诱发痛;热痛觉过敏;腹腔注射;神经病理性疼痛;大鼠;

67. muscular hyperalgesia

肌痛觉过敏

68. Keywords irritable bowel syndrome;visceral hyperalgesia;vanilloid receptor 1;abdominal withdraw reflex;

肠易激惹综合征;内脏痛觉过敏;辣椒素受体;腹部收缩反射;

69. Keywords irritable bowel syndrome;rat;harmful stimuli of colon;visceral hyperalgesia;

肠易激综合征;大鼠;结肠伤害性刺激;内脏痛觉过敏;

70. Keywords agmatine;analgesia;hyperalgesia;phosphorylated extracellular signal-regulated protein kinase;

胍丁胺;疼痛;痛觉过敏;磷酸化细胞外信号调节激酶;

71. Keywords Spinal Manipulation;Hyperalgesia;Inflammation;

脊柱操作;痛觉过敏;炎症;

72. Keywords Autologous nucleus pulposus;Hyperalgesia;Nerve conduction velocity;Histology;

自体髓核;痛觉过敏;神经传导速度;组织形态;

73. An Experiment Research of the Expression of GDNF in DRGs Derived by Auto-transplantation of Nucleus Pulposus and the Relationship between the Hyperalgesia and GDNF

自体髓核组织所致背根节GDNF表达以及与痛觉过敏之间关系的实验研究

74. Keywords protein kinase C;nitric oxide;Phorbol 12-Myrstate-Acetate;hyperalgesia;spinal cord;

蛋白激酶C;一氧化氮;佛波醇酯;痛觉过敏;脊髓;

75. Keywords Protein kinase C;Morphine dependence;Hyperalgesia;Injections;sspinal;

蛋白激酶C;吗啡依赖;痛觉过敏;注射;觉醒/脊髓;

76. To improve this hypothesis we must make sure that the expression change of GDNF in DRGs is related to hyperalgesia.

要证明此假说必须首先证明GDNF的表达变化与痛觉过敏有关联。

77. Time characteristics of changes of nitric oxide synthase activity in neurons of spinal cord posterior horn in rats with carrageenan-induced inflammatory pain and hyperalgesia

角叉菜胶炎性痛及痛过敏诱导大鼠脊髓后角神经元一氧化氮合酶变化的时间特征

78. Effects of estrogen on thermal hyperalgesia following chronic constrictive nerve injury in rats

雌激素对慢性神经病理性疼痛大鼠热痛觉过敏的影响

79. Differential actions of intrathecal nociceptin on persistent spontaneous nociception, hyperalgesia and inflammation produced by subcutaneous bee venom injection in conscious rats

鞘内注射孤啡肽对大鼠足底注入蜜蜂毒诱致长时程自发痛、痛敏和炎症的不同效果

80. Effect of intrathecal fluorocitrate on the mechanical and heat hyperalgesia in mice bearing bone cancer

鞘内注射氟代柠檬酸对骨癌痛小鼠机械痛敏和热痛敏的影响

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