mdr

mdr

1. Keywords VX 2 cell;MDR;retrovirus;gene transfer;

2细胞;多药耐药;逆转录病毒;基因转移;

2. Keywords K562/AO2 cell line;multidrug resistance（MDR）;matrine（MAT）;Medroxyprogesterone acetate（MPA）;

AO2细胞株;多药耐药;甲孕酮;苦参碱;

3. EBB has a strong reversal effect on MDR in MCF-7/ADR cell,which may be achieved by enhancing the arrestment of MCF-7/ADR cells at G_2/M phase and increasing intracellular drug concentration.

EBB对MCF-7/ADR细胞具有较强的逆转多药耐药作用,其可能的逆转机制在于增强ADR对耐药细胞在G2/M期的阻滞以及抑制P糖蛋白外排泵作用。

4. FCM is a good method to detect MDR protein and MRP function of bladder carcinoma,and DNR is a good probe to detect MRP function by FCM.

FCM是检测膀胱癌多药耐受蛋白质表达水平和 MRP功能水平的好方法 ,DNR是 FCM检测MRP功能的良好探针。

5. Mdr 1a gene knockout and drug transport

mdr 1a基因缺失与药物转运

6. The ratio of CR and the time of disease free surival (DFS) with the MDR 1 +/CD 34 + phenotgpe was significantly less than those of the MDR 1 -/CD 34 - phenotype.

MDR1 + / CD34+表型细胞较 MDR1 - / CD34-表型细胞缓解率、生存期、缓解期显著缩短。

7. Over expression of MDR1 and MRP genes is significantly involved in the mechanism of MDR phenotype in retinoblastoma.

MDR1和MRP基因的过度表达是Rb多药耐药现象发生的重要机制。

8. There was significant difference in the concentration of DNR between MDR 1 positive and MDR 1 negative cases before and after incubation.

MDR1阳性者骨髓细胞内柔红霉素浓度与阴性者相差显著。

9. Expression of mdr 1 gene and multidrug resistance of lung cancer

mdrl基因表达与肺癌多重抗药性关系的研究

10. EXPRESSION AND IMPLICATION OF MDR GENES AND MDR GENES-CODED PRODUCT IN LARYNGEAL PART OF PHARYNX MALIGNANT MELANOMA

MDR基因及MDR基因编码产物在咽喉部恶性黑色素瘤中表达及其意义

11. The relationship between abnormal MDR gene expression and chemotherapy response in lymphoid malignancies

MDR基因异常表达与淋巴系统恶性肿瘤化疗反应的相关性

12. MDR stands for multi-drug resistance, and it is one of the reasons why TB is back in the limelight.

MDR是指多药物抗药性，这个问题也是肺结核又重新受人们关注得原因之一。

13. Restoration of intracellular drug accumulation in MDR cell line K562r does not mean reversal of its drug resistance

MDR细胞株K562r细胞内药物积聚的恢复并不代表其抗药性的逆转(英文)

14. MDR TB can resist treatment with the antibiotics normally used to treat TB.

MDR结核可以耐受通常用来治疗结核的抗生素。

15. The MDR were developed to provide a legally accepted standard for labeling the amounts of nutrients in foods.

MDR被发展成标识食物营养素数量标签的合法可接受标准。

16. Incressing of occludin in SGC7901/VCR may be involved in gastric cancer MDR

Occludin在胃癌耐药细胞SGC7901中mRNA水平

17. Unfortunately, those infected with MDR have to be treated with less effective, more poisonous and more costly drugs.

不幸的是，那些感染了多药抗药性肺结核病的病人不得不服用效力较弱，但毒性更强，价格更高的药物。

18. Twonew bioactivities on reversing MDR and inducing apoptosis of luteal cell offered a clue innew drugs research and widened clinic application of droloxifene.

两种新的生物活性的发现对新药研究及扩大临床应用提供了实验依据。

19. Correlation between expression of mdr 1 gene and oncogenes in

人早幼粒白血病HL60细胞及其亚系中mdr－1基因和癌基因表达的关系

20. Keywords human leukemia K562/AO2 cell line;MDR;glucosylceramide synthase gene;RT-PCR;cell toxicity test;

人白血病K562/AO2细胞株;多药耐药;葡萄糖神经酰胺合酶基因;逆转录聚合酶链反应;细胞毒性试验;

21. Keywords human colon cancer cells;multidrug resistance;oxaliplatin;multidrug resistance（MDR）;small interfering RNA;TSG101 genes;

人结肠癌细胞;多药耐药;奥沙利铂;小干扰RNA;TSG101基因;

22. When to start with the strongest effect of the anti-virus drug, do we need to worry about any side effect such as MDR ( Mutual/should be multiple drug resistance).

什么时候进行治疗达到最强的抗病毒效果？我们需要考虑多重耐药的不良反应吗？

23. What alarms health officials is the potential for outbreaks of MDR to evolve into large XDR ones, creating the specter of an uncontrollable health menace.

什么警钟卫生官员是潜在爆发耐药演变成大型的%26,创造幽灵不受控制健康威胁。

24. However, R-verapamil (R-VPM),the isomeride of VPM is able to reversel MDR more effectively and safly, and has good perspective in clinical application.

从维拉帕米分离出的光学异构体R-型维拉帕米，在逆转肿瘤MDR时，更加高效安全，具有良好的临床应用前景。

25. These results suggest that PIC-BE is an effective anti-cancer compo und, and K562/ADM cell line with MDR has no resistance to it.

以上结果提示，PIC-BE是一种有效的抗肿瘤化合物，且已产生MDR的K562/ADM细胞对它不具耐药性。

26. However, DRO did not markedly increase ADR accumulation in K562. CONCLUSION: DRO had strong reversal effect on MDR in K562/A02, which was comparable to that of VRP, but the reversal effect was viadifferent pathways.

但DRO不能明显增加K562细胞内的ADR的浓度。 结论:DRO对K562/A02的MDR有较强的逆转活性,逆转强度与维拉帕米相当,其逆转机制有多种不同的途径。

27. This article sums up the new methods of reversing leukemic MDR.

作者就逆转白血病MDR方法的最新进展作一综述。

28. Keywords Children;Acute leukemia;MDR;P-gp;Real time fluorescent quantitation polymerase chain reaction;MDR function experiment;

儿童;急性白血病;多药耐药;P-糖蛋白;实时荧光定量聚合酶链反应;多药耐药功能实验;

29. Internalization of Antibody-targeted Immunonanoparticles into Human Hepatoma Cells and Its Reversal Effect on MDR

免疫毫微粒的内化作用及其逆转人肝癌细胞多药耐药性的研究

30. Keywords traditional Chinese medicine;tumor;MDR;reversion;

关键词中药;肿瘤;多药耐药;逆转;

31. Keywords Morpholines;Sphingolipids;Genes;MDR;P glycoprotein;Reverse transcriptase polymerase chain reaction;Flow cytometry;

关键词吗啡类;鞘脂类;基因;MDR;P-糖蛋白;逆转录聚合酶链反应;流式细胞术;

32. Keywords Multidrug resistance 1（ mdr 1）;Cochlea;Lateral wall;Extrusive traffic;

关键词多药耐药基因1;耳蜗;外侧壁;外向运输;

33. Keywords drug resistance;multiple;glycosphingolipids;genes;MDR;

关键词抗药性;多药;中性糖苷神经鞘脂类;基因;MDR;

34. Keywords Leukocytes;Genes;MDR;Polymerase chain reaction;Liver neoplasms;Neoplasm metastasis;

关键词白细胞;基因;MDR;聚合酶链反应;肝肿瘤;肿瘤转移;

35. Keywords multiple drug resistance pulmonary tuberculosis （MDR PTB）;L forms of mycobacterium tuberculosis （LMT）;clinical study;

关键词耐多药肺结核;结核分枝杆菌L型;临床研究;

36. Keywords tumor;multidrug-resistance（MDR）;traditio nal Chinese medicine;

关键词肿瘤;多药耐药;机制研究;中药;

37. Of 49 cases (3% of evaluable multidrug-resistant [MDR] TB cases) meeting the revised case definition for XDR TB, 17 (35%) were reported during 2000 to 2006.

其中有49个案例（佔所有可评估的多重抗药性(MDR)TB案例的3%）达到XDR TB的新定义标准，其中17个（35%）于2000年至2006年之间被通报；

38. Incubation with CCCP increased the accumulation of ciprofloxacin up to three-fold in MDR isolate but not in sensitive isolate.

加入能量抑制剂后，多重耐药株菌内的亲水性氟喹诺酮类药物蓄积浓度上升近3倍；

39. Most of the patients with XDR TB had been treated, incompletely, for MDR TB, the doctors found.

医生发现，患XDR结核的多数患者已被治愈，但对于治疗MDR还不够。

40. Keywords Ovarian neoplasms;Tumor cells;cultured;Drug resistance;neoplasm;Gene expression;Genes;MDR;

卵巢肿瘤;肿瘤细胞;培养的;抗药性;肿瘤;基因表达;基因;MDR;

41. Antisense MDR oligonucleotide combined with chemotherapy to inhibit drug resistant tumor cell growth

反义MDR寡核苷酸联合化疗药物抑制耐药肿瘤细胞

42. P gp represent an efflux transporter that extrudes a broad spectrum of anticancer drugs from the cell, which produce the MDR.

各型肾癌 P?gp 高表达，发挥药物排出泵的作用而产生 M D R。

43. Keywords Laryngopharynx;Malignant Melanoma;Multi-drug Resistance;MDR;Gene;

咽喉部;恶性黑色素瘤;多药耐药;MDR;基因;

44. Correlation of the expression of MDR genes and MDR genes-coded product with prognosis in laryngopharyngeal malignant melanoma

咽喉部恶性黑色素瘤多药耐药基因及其基因编码产物与预后关系的研究

45. During the development of MDR, epithelial to mesenchymal transition induced by Twist may be related to the enhanced invasion and metastatic potential of multidrug resistant breast cancer cells MCF-7/ADR.

在多药耐药乳腺癌细胞MCF-7/ADR中,其侵袭力增强可能与Twist介导的EMT发生有关。

46. The first approach in the United States was the establishment of the minimum daily requirements (MDR) by the Food and Drug Administration.

在美国第一个方法是由美国食品药品管理局(FDA)建立的最小日需要量(MDR)。

47. 7. Training for SR&MDR in sales office.

在营业所内做好业务人员的培训工作。

48. Keywords Genes;MDR;Neoplasm;residual;Leukemia;lymphocytic;acute;

基因;MDR;肿瘤;残余;白血病;淋巴细胞性;急性;

49. multidrug resistance(MDR)

多(种)抗药性[例如对肿瘤化疗的广谱抗性]

50. Muhidrug resistance (MDR)

多药耐药

51. Keywords multidrug resistance （MDR）;P-glycoprotein;immune electronic microscope;

多药耐药;P-170糖蛋白;免疫电镜;

52. Keywords ectromelia;multidrug resistance;immunity;P-glycoprotein;Colitis;multiple drug resistance （mdr） , gene;Dendritic cell;Multiple drug resistance （mdr）, gene;

多药耐药;P-糖蛋白;鼠痘病毒;免疫;结肠炎;树突状细胞;

53. mdr 1 gene

多药耐药基因

54. Multidrug resistance (MDR) is the most common cause in the failure of cancer chemotherapy.Drug transporters play an important role in multidrug resistance in cancer.

多药耐药性(MDR)是肿瘤化疗失败的最常见原因,药物转运蛋白在肿瘤多药耐药性中产生了重要的作用。

55. MDR cell

多药耐药细胞

56. MDR reversal

多药耐药逆转

57. multi-drug resistance (MDR)

多重耐药（MDR）

58. stp: s'il te plait lol: rire mdr: mort de rire kwa: quoi slt:...

如题。。。和法国人聊天或者和懂法语的聊天都可以用上哦。。要与时俱进呀。。哈哈。。

59. MDR gene expression in endometrial carcinoma and its clinical significance

子宫内膜癌MDR基因的表达与临床意义

60. memory data register (MDR)

存储器数据寄存器 存储数据寄存器

61. Clinical Significance of RT?PCR Assay for MDR?Gene Expression in Solid Tumors

实体肿瘤MDR1多药抗药基因表达RT-PCR检测的临床意义

62. However, multidrug resistance (MDR) presents an important obstacle for the success of the treatment.

对瘤组织而言,多药耐药是化疗失败的主要原因。

63. Fewer resistance tests exist for the newer, second-line drugs needed to treat MDR and XDR tuberculosis, and many of them are difficult to perform.

少阻力试验存在的更新,第二线药物来治疗和耐药结核病%26,很多人都难以做到的。

64. Although P gp expression is not the only mechanism of MDR, but determination of P gp expression might be helpful in making effort to overcome multidrug resistance of bladder cancer.

尽管P－gp表达不是引起多药耐受性的唯一机理，但它对克服膀胱癌的抗药性具有重要的临床价值。

65. MDR1-Pgp expression (multidrug resistance. MDR; P-glycoprotein, Pgp) was studied in 58 cases of primary breast carcinoma (PBC) by LSAB immunohistochemical technique.

应用免疫组化LSAB法对58例原发性乳腺癌组织进行了MDR1－Pgp检测。

66. Reverse transcription polymerase chain reaction (RT PCR) assay was used to detect the expression of MDR 1 mRNA and MRP mRNA in 35 patients. Meantime, Immunohistochemistry SABC technique was used to detect P glycoprotein(P gp) in 61 cases.

应用逆转录－多聚酶链式反应（RT－PCR）技术，检测了35 例喉癌患者MDR－1 m RNA、MRPm RNA 基因的表达，同时，应用免疫组化SABC法检测了61 例患者MDR－1 基因产物P－gp。

67. Study on the effect of Kanglaite injection on MDR human leukemia cell lines

康莱特注射液对多药耐药人白血病细胞株作用的实验研究

68. EXPRESSION LEVEL OF MDR 1 AND MRP IN PATIENTS WITH MALIGNANT BLOOD DISEASE AND ITS CLINICAL SIGNIFICANCE

恶性血液病患者MDR_1和MRP表达水平及其意义

69. The use of anti-cancer chemotherapy often leads to the rise of multidrug-resistant (MDR) tumors.We hae preiously reported the oerexpression of a 40 kDa protein (P-40) in seeral MDR tumor cell lines.

抗肿瘤药物的应用常常导致多耐药肿瘤细胞的增多，我们先前已经报道P-40在一些多耐药细胞株中的过度表达。

70. Adenovirus carrying antisense mdr1 RNA can partially reverse the MDR of HepG2/ADM cells and inhibit tumor growth by down-regulating mdr1 mRNA resulting in tumor cell apoptosis.

携带MDR1反义RNA重组腺病毒部分逆转HepG2/ADM的多药耐药,阻止肿瘤生长,下调MDR1转录水平,导致肿瘤细胞凋亡。

71. Multidrug resistance(MDR) has become the main hindrance of chemotherapy,and the reversal of MDR is the key point to improve curative effect of chemotherapy.

摘要 肿瘤细胞对化疗药物产生的多药耐药(MDR)已成为当前影响肿瘤化学治疗疗效的主要障碍,寻找低毒有效的MDR逆转剂是提高化疗疗效的关键。

72. Abstract: Multidrug resistance (MDR) is one of curses on oncotherapy study in recent years,the mechanisms of which are intricate extremely.

摘要： 肿瘤多药耐药(MDR) 是近年来肿瘤治疗研究的困扰之一，其产生机制非常错综复杂。

73. Abstract: Objective:To judge whether there was any effect of elemene in reversing the MDR in patients with advanced gastric cancer.

文摘:目的：观察榄香烯乳有无逆转晚期胃癌患者对化疗药物的耐药性。

74. Method:By using reverse transcriptase polymerase chain reaction (RT PCR), S, mdr 1 and LRP gene expression were studied in 46 de novo AML cases.

方法 :应用RT PCR法检测 4 6例初治AML患者的S、mdr 1和LRPmRNA表达的阳性率。

75. Methods:blc 2 and MDR expression were studied by immunohistochemical technique in 48 specimens of renal cell carcinoma tissues and in 10 normal renal tissues and their clinical significance was analyzed.

方法 :采用免疫组织化学 SABC法对 48例肾癌和 10例正常肾组织的石蜡包埋标本切片进行 bcl- 2和MDR- 1基因产物表达的统计研究。

76. Methods We induced human lung adenocarcinoma cell line A549 into multidrug resistant cell line A549/ADM through step-wise selection with adriamycin,establishing a MDR cell model;

方法 采用浓度递增法经阿霉素(ADM)诱导A549细胞系成为MDR细胞系A549/ADM，建立MDR细胞模型；

77. METHODS:The mannitol contents in the Cordy ceps samples collected from different growing areas were determined and compared ,and their MDR(Mutual Different Rate)was analyzed.

方法:对不同产地虫草样本的甘露醇含量进行直接比较和相互变异率分析。

78. Methods The effect of BSO on sensibility of anti-cancer drug in MDR LoVo/Adr cell was detected by MTT assay.

方法MTT法检测BSO对多药耐药LoVo/Adr细胞抗癌药物敏感性的影响;

79. METHODS The reverse transcription polymerase chain reaction(RT PCR) was used to detect expression of mdr 1 mRNA in 20 RCC and 5 normal kidneys.

方法应用逆转录?聚合酶链反应（RT?PCR）技术检测20例肾癌和5例正常肾组织mdr?1基因mRNA的表达。

80. Methods Human myeloid leukemia cells, K562 and NB4, were transduced by MDR retrovirus and the resistant cells were selected.

方法用MDR病毒转导人类白血病细胞K562和NB4，获得耐药细胞系；