neurotrophic

neurotrophic

1. In vitro the proliferation and differentiation of bone marrow stem cell (BMSc) after the treatment of neurotrophic factors (NTFs) will be evaluated and the possibility of applying NTFs in the bone tissue engineering will be discussed.

1)在细胞水平观察神经营养因子(NTFs)对体外培养的骨髓基质干细胞(BMSc)增殖和分化的作用，为神经营养因素应用于骨组织工程种子细胞研究打下基础；

2. OECs were dissociated from olfactory bulb of neonate SD rat and olfactory mucosa of majority SD rat which have the same function of excreting neurotrophic factor. 4.

3、取自SD乳鼠嗅球和取自SD成年大鼠嗅粘膜的OECs具有同样的分泌 神经营养因子的作用，其生物学活性大致相同。

3. NEUROTROPHIC EFFECT OF APP N-TERMINUS FRAGMENTS

APP N端片段的神经营养作用

4. brain derived neurotrophic factor(BDNF)

BDNF

5. The neurotrophic and myotrophic effect of CNTF ma y play an important role in the treatment of nerve-muscle injury and retrogress ion.

CNTF的神经和肌肉双重营养性能使其可能在神经肌肉损伤和退行性病变的治疗上发挥重要作用。

6. glial cell linederived neurotrophic factor(GDNF)

GDNF

7. Pigment Epithelium-Derived Factor(PEDF)has been found recently as a new neurotrophic factor.It expresses in many tissues.

PEDF是最近发现的一种神经营养因子,在许多组织均由表达。

8. precursor of brain-derived neurotrophic factor

proBDNF

9. Construction and characterization of recombinant adenoviruses expressing biologically active human brain-derived neurotrophic factor and neurotrophin-3.

[3]Chen Q(陈 谦), Wang JZ(汪家政), Liu H(刘 红), Wu Y(吴 燕), Fan M(范 明).

10. Ma ZC, Wu XL, Pan W, et al.Expression of brain-derived neurotrophic factor receptor trkB on NIH 3T3 cells[J].Life Sci Res, 2001, 5(3):265-9.

[6]马仲才,吴晓兰,潘卫,等.脑源性神经营养因子受体trkB在NIH 3T3细胞上的表达[J].生命科学研究,2001,5(3):265-9.

11. Ordinarily, when a person performs a task, a protein called brain-derived neurotrophic factor （BDNF） is secreted to the area of the brain that is associated with that activity.

一般来说，一个人执行一项任务时，相关大脑区域就会分泌一种名叫“脑源性神经营养因子”（BDNF）的蛋白质。

12. Soluble expression of recombinant human ciliary neurotrophic factor in e. Coli using lactose as inducer

乳糖诱导重组人睫状神经营养因子在大肠杆菌中的可溶性表达

13. Human ciliary neurotrophic factor

人睫状神经营养因子

14. Recombinant human Glial cell line-derived neurotrophic factor (rhGDNF)

人类重组的胶质细胞源性神经营养因子

15. Human brain-derived neurotrophic factor

人脑源性神经营养因子

16. Keywords spinal cord injury;ciliary neurotrophic factor;red nucleus neuron;HRP;

关键词脊髓损伤;睫状神经营养因子;红核神经元;HRP;

17. Keywords Spinal cord injury;Spinal cord edema;Ciliary neurotrophic factor;

关键词脊髓损伤;脊髓水肿;睫状神经营养因子;

18. Other researchers are using gene therapy instead of surgery to administer GDNF, hoping the delivered gene will provide a long-term supply of this neurotrophic agent.

其他的研究人员则利用基因疗法，来代替以手术方式投送GDNF，希望投送的基因能够长期供应神经生长因子。

19. The mechanism of stem-cell therapy includes cell-replacement, delivery neurotrophic factors and immunomodulation.

其治疗的作用机制主要分为3种：细胞替代、神经营养因子释放和免疫调节。

20. S-100B was also a neurotrophic factor.Suitable concentration of S-100B can induce nerve regeneration after trauma.

另外，S-100B具有神经营养因子的作用，适量浓度的S-100B可在损伤部位产生神经再生效应。

21. Insulin like growth factors also have a modulatory role in neuronal function.Insulin and neurotrophic factors including insulin ...

同样,胰岛素样生长因子对神经元功能也有一定的调节作用。

22. Neurotrophic effect of the Quchiling volatile oil-containing rat serum on the cultured newborn mouse cortical neurons

含去痴灵挥发油的大鼠血清对体外培养新生小鼠皮层神经元的营养作用

23. NGF have been found more than 50 years, it is the one of studied clearest neurotrophic factors,It is well known about it’sequence of amino acid and CDNA and gene position .

国内外关于NGF治疗目前尚处于基础和临床研究阶段，神经生长因子已发现50多年，是迄今为止研究得最清楚的一个神经营养因子，其氨基酸序列、cDNA序列、基因定位目前均已清楚。

24. In the process of development and regeneration of nervous system,it act as neurotrophic factor.

在神经系统发育和再生过程中,肝细胞生长因子作为神经营养因子发挥作用。

25. In the process of development and regeneration of nervous system, it act as neurotrophic factor.

在神经系统发育和再生过程中，肝细胞生长因子作为神经营养因子发挥作用。

26. The expression changes of glial cell line- derived neurotrophic factor mRNA after sciatic nerve cut in rats

坐骨神经切断后胶质细胞源性神经营养因子mRNA的表达变化

27. Initial Research of Primary Culture Embryonic Rat Spinal Cord Neurons and Its Expressions of Neurotrophic Receptors

大鼠胚胎脊髓神经细胞的原代培养及其神经营养素受体表达的初步研究

28. Construction and identification of brain derived neurotrophic factor gene cloned into a T-vector in rat

大鼠脑源性神经营养因子基因T载体的构建及鉴定

29. Kim H, Li Q, Hempstead BL, et al.Paracrine and autocrine functions of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in brain-derived endothelial cells[J].

孙春艳，胡豫，吴涛，等.多发性骨髓瘤细胞脑源性神经营养因子对血管新生作用的研究[J].中华血液学杂志,2005,26(10）：602-606.

30. It has powerful neurotrophic and neuroprotective activity.

它具有强大的营养和保护神经作用。

31. The Character of Glial Line-cell Derived Neurotrophic Factor mRNA Expression in a Facial Nerve-striking Model

家兔面神经撞击伤后胶质细胞源性的神经营养因子mRNA在面神经元中的表达特点

32. The expression of IR,IRS - 1 decreased in the hippocampal neuron in CPR rats,and early administration of neurotrophic factor-APP17 peptide could recover the expression of IR,IRS-1 to or approximately to the normal level.

心肺复苏大鼠海马神经元IR、IRS-1表达降低,复苏早期给予APP17肽干预可使其表达恢复正常或接近正常。

33. The brain's entorhinal cortex, which supports memory, normally produces brain-derived neurotrophic factor (BDNF); however, its production appears to decrease when Alzheimer's is present.

患者在患上阿尔兹海默病后，起记忆作用的大脑内嗅皮层所产生脑源性神经营养因子（BDNF）会减少。

34. Preincubation of the cultures with ciliary neurotrophic factor (CNTF) for 24 h promoted neuronal survival and decreased the LDH efflux and the level of NO induced by ionomycin.

提前24 h给予不同浓度CNTF, 均能提高神经元的存活率, 减少LDH漏出, 其作用呈剂量依赖性;CNTF可降低ionomycin引起的NO含量升高;

35. Objective To investigate the expression of brain-derived neurotrophic factors (BDNF) in gliomas of human, and explore the relation between BDNF and pathologic grading and tumorigenesis of gliomas.

摘要目的探讨脑源性神经营养因子(BDNF)在人脑胶质瘤内的分布与表达，并探讨它们与肿瘤病理分级的关系及其在肿瘤发生过程中的作用。

36. Brain-derived neurotrophic factor (BDNF) is one of the neurotrophic factors.BDNF has many biological effects on neurons of peripheral and central nervous system.

摘要脑源性神经营养因子(BDNF)是神经营养因子家族中的一员，BDNF对周围和中枢神经元有广泛的生物学作用。

37. Abstract： Brain-derived neurotrophic factor （BDNF） can increase the excitability of hippocampus by activating its receptor tyrosine kinase B and then result in temporal epilepsy.

摘要： 脑源性神经营养因子（BDNF）激活其受体酪氨酸受体激酶B，使海马兴奋性增高，从而促使颞叶癫痫产生。

38. Methods: The right L4,L5 nerve roots of infant SD rats postnatal 3 weeks were transected and the proximal stumps were treated with neurotrophic factor deriving from Schwann cell or saline for 4 weeks.

方法:选出生3周sD鼠高位切断L4、L5神经根,神经近侧断端应用雪旺细胞源神经营养因子或生理盐水,4周后观察损伤神经根背根节感觉神经元的存活率和形态学变化。

39. Methods Administration of sufficient dose of corticosteroids,vasodilators,vitamins and neurotrophic drugs in 38 cases of traumatic optic neuropathy in the early stage and its effect were observed.

方法将38例(38眼)外伤性视神经损伤早期应用大剂量皮质类固醇、脱水剂、血管扩张剂、维生素及神经营养药物治疗结果进行分析。

40. Methods Nylon column and MACS were used to isolate CD4 + /CD8 + T lymphocytes. The expression of neurotrophic receptors was detected by RT PCR.

方法应用尼龙毛法分离出T细胞 ,磁式细胞分离法 (MACS)分离CD4 + /CD8+ T细胞亚群 ,再以RT PCR法研究 4种神经营养素受体在两种T细胞亚群上的表达。

41. Recent data have suggested neuroprotective and perhaps even neurotrophic roles for erythropoietin.

最新资料认为促红细胞生成素在神经保护和神经再生方面亦发挥作用。

42. This paper reviewed the effect of some major neurotrophic factors on diabetic neuropathy and their application in clinical treatment.

本文对一些主要的神经营养因子对糖尿病性神经病理变性及再生作用，以及神经营养因子在临床糖尿病性神经变性的应用研究作-综述。

43. To construct a recombinant plasmid containing protein transduction domain(PTD) and brain derived neurotrophic factor(BDNF) fusion gene and express in E.

构建含蛋白转导结构域(PTD)与脑源性神经营养因子(BDNF)融合基因的质粒,并在大肠肝菌中表达。

44. In addition, EPO can across blood-brain barrier in combination with the specific receptors.And this is the advantage that many neurotrophic factors do not have.

此外,EPO能通过与特异性受体结合透过血脑屏障,这是许多神经营养因子所不具备的优势。

45. Keywords hippocampi;carrier;neuron neurotrophic;factor;

海马;载体;神经细胞;神经营养因子;

46. Hippocampal size and the numbers of neurons and glia are decreased, possibly reflecting reduced neurogenesis due to elevated cortisol levels or due to reduced brain-derived neurotrophic factor.

海马大小和神经元数目和神经胶质减少（小），可能反应了神经发生减少，由于皮质醇水平提高或由于脑源性神经营养因子的减少。

47. Brain-derived neurotrophic factor mRNA expressions in rat brain induced by short-term in vivo exposure to deltamethrin

溴氰菊酯对大鼠脑组织脑源性神经生长因子表达的诱导

48. The article reviews the discovery,effect and mechanism of these neurotrophic factors that secreted by BMSCs no matt...

现就骨髓基质细胞在体内或体外分泌的多种神经营养因子的发现、作用及机制进行综述。

49. Alterations in the neurotrophic levels either due to age, genetic background or other factors might contribute to neurodegeneration.

由年龄、基因突变或其他因素导致的神经营养因子水平的改变可以导致神经元退行性变。

50. Delaying of denervated muscle atrophy by means of gene transfer of ciliary neurotrophic factor by electroporation

电穿孔介导睫状神经营养因子基因转染延缓失神经肌萎缩

51. Keywords Baisong tablets;Hippocampus;Ciliary neurotrophic factor;

白松片;海马;睫状神经生长因子;

52. And now the basic strategy of gene therapy in repairing peripheral nerve injury is to make the gene,which encodes neurotrophic factor express constantly in target cell in vivo by vectors.

目前,基因治疗修复周围神经损伤的基本策略是利用载体工具将编码神经营养因子的基因转入靶细胞,使之在体内持续表达,进而达到治疗效果。

53. Objectives:To compare the effect of glial cell line derived neurotrophic factor(GDNF) and methylprednisolone(MP) on intracellular free calcium([Ca 2+ ]i) and capacity of containing water(CCW) after spinal cord injury(SCI).

目的 :比较胶质细胞源性神经营养因子 (GDNF)与甲泼尼龙 (MP)对脊髓损伤组织细胞内游离钙及水含量的影响。

54. The effect of ciliary neurotrophic factor (CNTF) on the denervetde skeletal muscle atrophy was studied by detecting fiber cross-sectional areas soleus muscle (SOL) and extensor digitorum longus (EDL) in nerve transected SD rats.

目的 :通过测定SD大鼠坐骨神经离断后比目鱼肌 (SOL)和趾长伸肌 (EDL)肌纤维横截面积 ,观察持续给睫状神经营养因子 (CNTF)对去神经骨骼肌萎缩的影响。

55. Objective To construct a kind of engineered cells that can secrete human glial cell line derived neurotrophic factor (GDNF) and study its possible effects on genetic therapy of Parkinsons disease.

目的 构建携带大鼠胶质细胞源性神经营养因子(GDNF)基因的真核细胞表达载体，为应用GDNF进行如帕金森综合征之类的神经元退化性疾病的基因治疗打基础。

56. AIM: To understand the mechanism of neurotrophic action of neuropeptide ZNC(C)PR and its effect on which could affect both growth and apoptosis of C6 cells.

目的:研究神经肽ZNC(C)PR通过C6细胞发挥的神经营养作用和机制。

57. AIM:To observe whether the Schwann cell derived neurotrophic factor (SDNF) given by muscle injection could improve the quality of the regenerated nerve after end-to-side neurorrhaphy.

目的:观察分析肌肉注射许旺细胞源神经营养因子能否提高端侧吻合后再生神经的质量。

58. Objective To study the effect and mechanism of ciliary neurotrophic factor (CNTF) on the spinal motor neuron death and degeneration following peripheral nerve lesion in the rat.

目的探讨周围神经损伤后睫状神经营养因子（CNTF）对脊髓运动神经元的保护作用及其作用机理。

59. Objective To explore the changes of brain-derived neurotrophic factor(BDNF) after repeated febrile seizures (FS).

目的探讨大鼠反复高热惊厥(FS)后脑源性神经营养因子(BDNF)的变化。

60. Objective To investigate the effects of glial cell line derived neurotrophic factor in human inflammatory pulp.

目的探讨胶质源性神经营养因子(GDNF)在人炎症牙髓中的表达及意义。

61. Objective To study the pattern of the distribution of NGF (nerve growth factor)and BDNF(brain - derived neurotrophic factor) in adult rat motocortex following complete spinal cord transection (SCT) .

目的探讨脊髓全横断后神经营养因子在运动皮质内的分布规律,为临床应用神经生长因子治疗脊髓损伤提供实验依据。

62. Objective To investigate the role of ciliary neurotrophic factor (CNTF) in injury of central neuron.

目的研究睫状神经生长因子(CNTF)在中枢神经元抗损伤中的作用及机制。

63. Objective To study the protective effects of Schwann cell derived neurotrophic factor (SDNF) on motoneurons of spinal anterior horn from spinal root avulsion induced cell death.

目的研究雪旺细胞源神经营养因子(SDNF)对臂丛神经根性撕脱所致前角运动神经元死亡的保护作用。

64. Objective To observe the protective effects of topical application of glial-cell-derived neurotrophic factor (GDNF) on facial motoneurons following facial nerve injury in adult rats.

目的观察大鼠面神经低位切断伤后，大鼠面运动神经元死亡的时间进程和胶质细胞源性神经营养因子(GDNF)局部应用对伤后面运动神经元的作用。

65. Aim To observe the effects of APP17 peptide on the changes in the levels of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) in rat brain induced by cardiopulmonary resuscitation (CPR).

目的观察心肺复苏术后大鼠海马神经元神经生长因子(nerve growth factor,NGF)、脑源性神经营养因子(brain-derived neurotrophic factor,BDNF)表达的变化,以及APP17肽对NGF、BDNF表达的影响。

66. To study the ultr a structure localization of Schwann cell （SC） derived neurotrophic factor （SDNF） in Schwann cells.

目的观察许旺细胞源神经营养因子的超微结构定位，探索其在神经、皮肤和肌肉中的分布以及神经损伤前后量的变化。

67. Objective In order to observe the growth characteristics of hippocampus neural cells of neouatal rats cultureal with carriers(made by ourselves)carrying neurotrophic factors.

目的采用自制的载有神经细胞营养因子的载体与新生大鼠海马神经细胞共同培养,观察其生长特点。

68. Objective: To investigate the effect of neurotrophic factors derived from Schwann cell (Sc?NTFs) on injured spinal cord.

目的：观察雪旺细胞源神经营养因子（Sc－NTFs）对损伤脊髓组织的作用。

69. ciliary neurotrophic factor (CNTF)

睫状神经营养因子

70. Keywords Ciliary neurotrophic factor;Type 2 diabetes;Obesity;Leptin resistance;

睫状神经营养因子;2型糖尿病;肥胖;瘦素抵抗;

71. Effects of gene transfer of ciliary neurotrophic factor on delaying of denervated muscular atrophy

睫状神经营养因子基因转染延缓失神经肌萎缩的作用

72. Effects of ciliary neurotrophic factor on processes regrowth of purified rat retinal ganglion cells in vitro

睫状神经营养因子对纯化培养大鼠视网膜神经节细胞突起再生的影响

73. It is discovered that astrocytes and neurons secret many neurotrophic factors (NTFs) thatregulate the survival, differentiation and maintenance of function in neurons after stroke.

研究发现,脑缺血后,神经胶质细胞和神经元分泌大量具有神经营养活性的神经营养因子(NTFs),NTFs 能够从多途径对抗脑缺血损伤并促进损伤后神经元的修复。

74. Research has shown that exercise can increase levels of a substance called brain-derived neurotrophic factor (BDNF), which encourages growth, communication and survival of neurons.

研究表明运动能够增加一种叫做脑源性神经营养因子的物质(BDNF)的水平，这种物质可以激励神经元的生长，增加联通和生存率。

75. Many studies reported suggest both neuronal precursor cells before innervation of target fields and the neurons of adult animal coexpress neurotrophic factors and their receptors, implying that autocrine and paracrine modes of NTFs exit.

研究表明，无论是靶组织联系建立以前的神经元前体细胞，还是成年后的神经元，均有神经营养因子与其受体的共同表达，提示有神经营养因子自分泌和旁分泌存在的可能性。

76. A lot of neurotrophic factors (NTFs) including NGF, BDNF, FGF, and CNTF can promote RGCs survival both in vitrol and in vivo.

研究证实多种NTFs(如NGF、BDNF、FGF、CNTF)对体外培养及视神经横断伤后RGC的存活有明显促进作用，为轴突再生提供了前提条件。

77. Keywords Nitropropionic Acid;Huntington s Disease;Neurotrophic Factor;Rat;

硝基丙酸;亨廷顿病;神经营养因子;大鼠;

78. The smrvival of neurons in vitro is an important indcx to evalutate thc trophic effect of neurotrophic factors (NTFs).

神经元在体外的存活是衡量一种营养因子有无神经营养作用的重要指标之一。

79. Nerve regeneration-related neurotrophic factor

神经再生相关营养因子

80. Nerve growth factor is the typical representative of neurotrophic factor family,which has conspicuous effect on nervous system.

神经生长因子(NGF)是神经营养因子家族的典型代表,为一种碱性蛋白,是神经系统中最重要的生物活性分子之一,有明显的中枢效应。