nucleosome

nucleosome

1. Anti - nucleosome antibody (ANA)

ANA

2. DNA wraps around histones in left-handed way and forms nucleosome structure.Many nucleosomes are linked together like “prayer beads”.

DNA分子以左手的方式缠绕在组蛋白分子上，形成核小体结构，多个核小体象“念珠”一样串联。

3. Keywords organ or system damage;peripheral blood mononuclear cell;apoptosis;lupus erythematosus, systemic;antigens, CD95;nucleosome;antinucleosome antibody family;

关键词器官/系统损害;外周血单个核细胞;脱噬作用;红斑狼疮;系统性;抗原;CD95;核小体;抗核小体抗体家族;

4. Keywords Nucleosome;Lupus erythematosus;systemic;Nephritis;Enzyme-linked immunosorbent assay;

关键词核小体;红斑狼疮;系统性;肾炎;酶联免疫吸附测定;

5. half nucleosome model

半核粒模型

6. positioned nucleosome

取位核小体

7. The relationship between nucleosome and clinical features of systemic lupus erythematosus

可溶性核小体与系统性红斑狼疮临床表现及免疫学指标的关系

8. Micrococcal nuclease treatment indicates that the remodeling of the demembranated sperm chromatin has occurred and the structure of nucleosome is formed during nuclear reconstitution.

同时，利用小球菌核糖核酸酶处理的结果表明，去膜精子在此非细胞体系中发生了结构改建并且在重建过程中形成了核小体结构。

9. 7．Which combinations of histones form“histone-fold”dimers with each other in the nucleosome?

在核小体中，每个组蛋白二聚体分别由哪几种组蛋白组成？

10. During histone exchange, chromatin remodeling complex facilitates histone variant deposition into nucleosome, and different variants have diverse deposition pathways.

在组蛋白替换过程中，组蛋白变体是通过相应的染色质重构复合物组装人核小体，不同的变体有着不同的组装途径。

11. We numerically simulate the interaction between DNA and a histone.And we get the nucleosome structure.DNA wraps around histone about 2 loops.

在适当的参数条件下，得到了合理的结果，即DNA能够缠绕组蛋白约两圈形成准核小体结构。

12. If H1 is located at the linker, it could "seal" the DNA in the nucleosome by binding at the point where the nucleic acid enters and leaves (see Figure 19.4).

如果H1位于连接区，它通过固定在核酸进出位点，能封住核小体内的DNA（见图27.4）。

13. To adapt to various states of chromatin, corresponding histone variants are incorporated in nucleosome, and certain modifications also occur on the variants tails.

对于不同状态的染色质，核小体中会组装人相应的组蛋白变体，并且各种组蛋白变体的尾部也能发生多种修饰。

14. To adapt to various states of chromatin, corresponding histone variants are incorporated in nucleosome, and certain modifications also occur on the variants’ tails.

对于不同状态的染色质，核小体中会组装入相应的组蛋白变体，并且各种组蛋白变体的尾部也能发生多种修饰。

15. , Zhang, B. and Zhai, Z. (1994) Chromatin and nucleosome organizations and DNA replication on nucleus reassembled in vitro using purified exogenous DNA and Xenopus egg extracts.

张博，翟中和，(1992)，非细胞体系核重构过程的超微结构研究。

16. Brownian Dynamics Simulation of Nucleosome Formation in Microfluidic Chip

微流控芯片中核小体构象的布朗动力学模拟

17. Anti- nucleosome antibody

抗核小体抗体

18. Abstract : Histones, as basic components of nucleosome , are essential to chromatin structure and function.

摘要 ： 组蛋白作为核小体的基本组分，是染色质的结构和功能必需的。

19. Histones, as basic components of nucleosome, are essential to chromatin structure and function.

摘要组蛋白作为核小体的基本组分，是染色质的结构和功能必需的。

20. Abstract: The nucleosome, the structural unit of chromatin, is known to play a central role in regulating gene transcription from promoters.

摘要：核小体作为染色质的结构单位，在基因启动子区域调节基因转录中具有重要的作用。

21. We numerically study the interaction between DNA and histone using a Brownian dynamics simulation. The process of nucleosome formation is shown in detail.

文章作者运用布朗动力学,数值模拟了DNA与组蛋白相互作用最终形成核小体的动力学过程,揭示了DNA与组蛋白相互作用的详细图景,并提出了组蛋白八聚体旋转模型,以解释这一过程.

22. nucleosome free

无核小体

23. nucleosome free region

无核小体区域

24. non-phased nucleosome

未取相核小体

25. The nucleosome, the structural unit of chromatin , is known to play a central role in regulating gene transcription from promoters.

核小体作为染色质的结构单位，在基因启动子区域调节基因转录中具有重要的作用。

26. nucleosome dynamics

核小体动态

27. nucleosome phasing

核小体定相

28. The nucleosome is the basic unit of the chromatin in all eukaryotes.Nucleosome assembly is fundamental in various cellular processes such as DNA replication, repair, recombination and transcription.

核小体是真核生物染色质的基本单位，其组装的重要意义体现在广泛的细胞学过程中，诸如DNA 复制、修复、重组以及转录。

29. nucleosome core

核小体核心

30. nucleosome core particle

核小体核心颗粒

31. nucleosome fiber

核小体纤维

32. nucleosome organization

核小体组构

33. Nucleosome assembly protein 1 (NAP1) is conserved from yeast to human and facilitates in vitro the assembly of nucleosomes as a histone chaperone.

核小体组装蛋白(Nucleosome Assembly Protein 1, NAP1)是真核生物中非常保守的、在体外能够促进核小体组装的一种组蛋白分子伴侣。

34. Nucleosome Assembly Protein 1 (NAP1) is considered to be a histone chaperone involved in nucleosome assembly.

核小体组装蛋白1（NAP1）被认为是参与到核小体组装过程中的组蛋白分子伴侣。

35. features of nucleosome structure appear to be similar in all eukaryotes.

核小体结构的一般特性似乎在所有的真核生物中都很相似。

36. nucleosome displacement

核小体置换

37. nucleosome assembly

核小体装配

38. nucleosome mobility

核小体运动性

39. nucleosome positioning

核小体选位

40. nucleosome remodeling

核小体重塑

41. nucleosome reconstitution

核小体重建

42. nucleosome reorganization

核小体重构

43. nucleosome spacing

核小体间距

44. Keywords nucleoplasmin;chaperone;nucleosome assembly;chromatin remodeling;

核质蛋白;分子伴侣;核小体装配;染色质重建;

45. Each nucleosome contains both DNA and four of the five kinds of histones

每一个核体不仅含有DNA，而且含有五种组织蛋白中的四种。

46. Cloning and Expression of a Putative Tobacco Nucleosome Assembly Protein cDNA and Purification of Its Product

烟草拟核小体组装蛋白cDNA的克隆、表达及其蛋白产物的纯化

47. Then, nucleosome chain is compressed into 30 nm solenoid structure.

然后，核小体链再进一步压缩形成30纳米的螺线管结构。

48. Recent advances have allowed nucleosome dynamics on promoters to be studied in real time, dramatically changing how we think about gene regulation on chromatin templates.

目前的进展已经能够实时地监控启动子上核小体的动力学改变，戏剧性地改变了我们对染色体上基因调控的认识。

49. Histones, as the basic components of nucleosome, are essential to chromatin structure and function.

组蛋白作为核小体的基本组分，是染色质的结构和功能必需的。

50. altered nucleosome region

结构改变的核小体区域

51. A Preliminary Study on Nucleosome in the Most Primitive Eukaryote-Giardia lamblia

蓝氏贾第虫核小体的初步研究

52. Construction and expression of the attenuated Salmonella typhimurium strain expressing the nucleosome Th epitope

表达核小体Th表位减毒鼠伤寒沙门菌株的构建

53. These modifications tend to colocalize in the genome and correlate with each other at an individual nucleosome level.

这些修饰在基因组中趋向于局部化，并在单核小体层上相关。

54. These variants change the conformation and stability of nucleosome to facilitate transcriptional activation or deactivation, DNA repairing, heterochromatin formation, and others.

这些变体通过改变核小体的空间构象和稳定性，决定基因转录的激活或沉默，DNA的修复，染色体的异染色化等。