phocomelia

phocomelia

1. (3)teratogenic environmental factors,such as Phocomelia and alcohol syndrome;

(4)基因环境交互作用,包括唇腭裂、先天性心脏病、神经管畸形等。

2. 1.It was removed from the market in 1961 after it was associated with an epidemic of severe birth defects: phocomelia and amelia.

1961年,明确发现沙利度胺可引起婴儿海豹肢畸形及无肢畸形,导致该药迅速撤出市场。

3. Roberts-SC phocomelia syndrome

Roberts-SC短肢畸形综合征

4. Phocomelia of upper limb

上肢短肢畸形

5. Proximal phocomelia of upper limb

上肢近侧短肢畸形

6. Distal phocomelia of upper limb

上肢远侧短肢畸形

7. Phocomelia of lower limb

下肢短肢畸形

8. Proximal phocomelia of lower limb

下肢近端短肢畸形

9. Distal phocomelia of lower limb

下肢远端短肢畸形

10. unilateral lower limb phocomelia

单侧下肢海豹肢畸形

11. Complete phocomelia of upper limb

完全性上肢短肢畸形

12. Complete phocomelia of lower limb

完全性下肢短肢畸形

13. By 1960 an extremely rare type of birth defect was appearing across Germany. Babies were born with hands and feet attached directly to the body a condition known as phocomelia.

导至这一悲剧的原因:“反应停”在大鼠身上的通过的动物试验试验结果用于临床是有瑕疵的,大鼠身上有人所没有一种的酶,它使大鼠不会产生的海豹畸形儿。

14. complete phocomelia

海豹肢畸形, 短肢畸形

15. 16. And still the cause of the phocomelia outbreak remained unknown.

然而,畸形儿病例大量发生的原因不得而知。

16. phocomelia shear wall

短肢剪力墙

17. distal phocomelia

远端短肢畸形

18. Callus Lengthening for Phocomelia after Septic Arthritis of the Hip at Infancy

骨痂延长术治疗婴幼儿期化脓性髋关节炎后遗短肢畸形

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