pseudogene

pseudogene

1. This pseudogene (named makorin1-p1) is a greatly shortened copy of makorin1, an ancient gene that mice share with fruit flies, worms and many other species.

makorin1是小鼠、果蝇、蠕虫以及许多其他物种都共有的古老基因。

2. Y-linked zinc finger pseudogene

Y连锁假锌指基因

3. But this past May a group of Japanese geneticists led by Shinji Hirotsune of the Saitama Medical School reported their discovery of the first functional pseudogene.

不过2003年5月，由日本埼玉医科大学遗传学家广常真治所领导的团队，报告说他们发现了第一个具有功能的伪基因。

4. 5．What is a pseudogene, and how do you recognize one?

什么是假基因？你如何识别出假基因？

5. But if the gene copy contains disabling typos or is missing pieces of the original, such as the promoter, it will become a pseudogene.

但如果基因出现短缺（像是缺失启动子）或序列发生错误使基因损坏，它们就成了伪基因。

6. On Research Progress of Pseudogene

假基因的研究进展

7. Keywords adrenoleukodystrophy;molecular diagnosis;[QX（Y9]ABCD1 gene;pseudogene;amplification refractory mutation system;

关键词肾上腺脑白质营养不良;分子诊断;ABCD1基因;假基因;扩增阻滞突变系统;

8. Among the new genes (alleles), CYP4C23 may be a pseudogene, CYP4H13 has a retained intron 58 nucleotides in length, and CYP4J4V1 has a stop coden (TAG) in frame near the 3'-end.

其中CYP4C23可能是一 个假基因，CYP4H13具有一段58个碱基长度的内含子，CYP4J4V1在近3’端具有一个终止密码子TAG.

9. In one extreme case, a single ribosomal protein gene known as RPL21 has spawned more than 140 pseudogene copies.

在一个极端的例子当中，有一个称为RPL21的基因，竟然衍生出140多个伪基因。

10. Careful sequence comparisons have shown that one cow gene for a ribonuclease enzyme was a pseudogene for much of its history but appears to have been reactivated during recent evolutionary time.

在仔细比对序列之后，科学家发现牛的某个核糖核酸酶基因，在漫长的演化中一直是个伪基因，直到最近才重新活化。科学家还发现，个体间的伪基因有些微的差异。

11. A deep divergence was observed within the Weixi population, which was confirmed after excluding the possibility of it being a nuclear pseudogene.

在排除了核线粒体假基因存在的可能性之后，滇金丝猴维西群体内部被确认存在着两个序列分歧较大的分枝。

12. Cloning and sequence analysis of a pseudogene of liver regeneration augmenter in rats

大鼠肝再生增强因子假基因的克隆化与序列分析

13. Detection of the Micrometastases in Peripheral Blood of Patients with Bre ast Cancer by Means of Reverse Transcriptase-Polymererase Chain Reaction for Cytocreatin 19 Free of Pseudogene Interference

无假基因干扰的CK19 RT-PCR方法检测乳腺癌外周血微转移

14. Conclusion The presence of processed pseudogene usually interferes in the experimental protocol in RT-PCR.This problem can be resolved with the method aforementioned.

结论在运用RT-PCR法分析哺乳动物基因表达时常存在假基因的干扰，以上方法可有效地发现和克服这种干扰作用。

15. Distribution of poly(ADP-ribose) polymerase pseudogene polymorphism and association with susceptibility to lung cancer in Chinese people

聚腺苷二磷酸核糖聚合酶假基因多态性分布及其与肺癌易感性的关系

16. Keywords Liver regeneration;Polymerase chain reaction;Rats;Pseudogene;

肝再生;多聚酶链反应;大鼠;假基因;

17. Keywords Keratin 14;Molecular diagnosis;Pseudogene;Special amplification;

角蛋白14;分子诊断;假基因;特异性扩增;

18. Others are copies of a gene that has so evolved over time, the pseudogene's sequence may reflect an older, earlier version of its parent.

还有些基因已随岁月改头换面，伪基因序列则反映出较古老的版本。

19. These anomalies could arise if random mutation reversed the disablement that originally produced the pseudogene.

这种变异型的产生，可能是因为原本让基因失去功能、变成伪基因的缺损，因随机突变而修复了。