silencing

silencing

1. The study showed that 5-azacytidine could be used as a potential mutagen in overcoming of transgene silencing and creation of the transgenic plants with elite agronomic traits.

5-氮胞苷作为一种弱诱变剂在克服转基因沉默及创造具优良农艺性状的转基因植物中具有一定的应用价值。

2. Keywords DNA methylation;DNA methyltransferases;transcriptional silencing;

DNA甲基化;DNA甲基转移酶;转录抑制;

3. DNA Methylation, Histone Modifications and Genes Silencing

DNA甲基化、组蛋白修饰与基因沉默

4. DNA methylation plays a key role in transgene silencing.

DNA甲基化是引起外源基因沉默的主要原因。

5. DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription, induce gene silencing at the participation of many regulators.

DNA甲基化由DNA甲基转移酶催化 ，在多种调节因子的参与下，与组蛋白修饰相互作用，抑制基因转录，导致基因沉默。

6. DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription,induce gene silencing at the participation of many regulators.

DNA甲基化由DNA甲基转移酶催化,在多种调节因子的参与下,与组蛋白修饰相互作用,抑制基因转录,导致基因沉默。

7. DNA methyltransferase inhibitor 5-Aza-CdR can induce demethylation in the promoter region of RASSF1A. It can also reverse epigenetic transcriptional silencing caused by methylation and induce the re-expression of RASSF1A in QBC-939.

DNA甲基转移酶抑制剂5-Aza-CdR能够诱导RASSF1A基因启动子区域去甲基化,并通过该机制诱导RASSF1A基因在人胆管癌细胞系QBC-939中的表达。

8. Our findings, for the first time, revealed a new biological activity for eIF5A as the regulator of p53. Overexpression of eIF5A or its EFP domain resulted in up-regulation of p53, and silencing eIF5A by siRNA reduced p53 protein level.

eIF5A过表达能导致p53蛋白上调,而eIF5A siRNA则通过抑制内源性eIF5A的表达而下调p53蛋白水平。

9. The results of FACS indicated that apoptotic rate of ovarian cacinoma cells was obviously increased after silencing AKT2 by co-transfection.

FACS结果显示,共转染沉默AKT2基因后,细胞凋亡率明显增加(P<0.05)。

10. Initial Noise and Noise Silencing Life of NSK Bearing Used in Househould Elctrical Appliance

NSK家电轴承的初期静音及静音寿命

11. Silencing HPV-16 E6 Gene in Human Cervical Cancer CaSki Cell Line by RNA Interference

RNAi沉默人宫颈癌CaSki细胞HPV-16 E6基因表达的研究

12. RNA interference (RNAi) is a post-transcriptional gene silencing induced by introduction of double-stranded RNA(dsRNA). It is a powerful tool for silencing gene expression.

RNA干扰(RNA interference,RNAi)是由双链RNA(double-stranded RNA,dsRNA)引发的转录后基因沉默机制(post-transcriptional gene silencing,PTGS),它是沉默基因表达的一个十分有效的手段。

13. RNA interference(RNAi) is a powerful gene tool targeting post-tra- -nscriptional gene silencing, which has recently been used to silence gene expression in various species.

RNA干扰(RNAi)是一种转录后基因沉默(Post-transcriptional gene silence,PTGS)的基因阻断技术,近年来被广泛应用于哺乳动物细胞抑制基因表达。

14. Induction of silencing effect of Alzheimer disease familial Swedish mutant APP by RNA interference

RNA干扰对阿尔茨海默病家族性瑞典型APP突变的沉默作用(英文)

15. RNA interference(RNAi)is a process through which double-stranded RNA(dsRNA)induces the sequence-specific post-transcriptional silencing of gene.

RNA干扰是一种转录后基因沉默现象,可通过双链诱导使靶基因失活。

16. Effect of silencing mdrl gene by RNA interference with adriamycin on proliferation of SKOV_3/ADM

RNA干扰沉默mdrl基因联合阿霉素对卵巢癌耐药细胞株SKOV_3/ADM增殖的抑制作用

17. RNA silencing

RNA沉默

18. RNA silencing is a recently identified mechanism that influences expression of genes in a wide variety of organisms, including fungi, nematodes, fruit fly (Drosophila), plants and mammalian cells.

RNA沉默(RNA silencing)是一种在真核生物体内普遍保守的，发生在RNA水平的，基于核酸序列特异性的相互作用来抑制基因表达的调控机制。

19. RNA Silencing and Its Application in Plant Gene Function Research and Crop Improvement

RNA沉默及其在植物基因功能研究和作物改良中的应用

20. suppression effect of RNA silencing

RNA沉默抑制现象

21. RNA-induced silencing complex

RNA诱导沉默复合体

22. siRNA-mediated Silencing of ClC-2 Gene Inhibits Proliferation of Human U-87 Glioma Cells

siRNA干扰ClC-2表达对人胶质瘤U-87细胞增殖的抑制作用

23. SET domain proteins of SUV3-9H family specifically methylate the residue lysine 9 of histone H3, resulting in gene silencing.

Su(var)3-9家族的SDP专一甲基化组蛋白3第9位赖氨酸(H3K9),从而导致基因沉默(gene silencing)。

24. Target of methylation-induced silencing gene

TMS1／ASC基因

25. "It gets inactivated and it's probably the same sort of RNA-directed silencing mechanism." he explains.

“它被灭活了并且很可能与RNA定向沉默机制方式相同”他解释到。

26. "I wasn't worried about silencing people.

“我不会为那些对我保持沉默的球迷犯愁。

27. "Silencing Shot" now does only 50% of weapon damage instead of 75%.

“沉默射击”现在造成50%武器伤害而不是之前的75%。

28. On one hand, the options are finding the flightless bird and realizing our own frailty, or losing the American mouth and silencing ourselves about it.

一种是，我们找到了那只折翅的鸟并发现它其实是我们自身脆弱的化身；

29. God loses for me an apple, is silencing, both hands hang down incapably, does not want to go to the heaven.

上帝丢给我一个苹果，沉默着，双手无力低垂，不想去天堂。

30. TMV CP;different constructs;methylation;post transcriptional gene silencing;watermelon;virus diseases;transformation;resistance.

不同结构形式;甲基化;转录后基因沉默;西瓜病毒病;转基因;抗病性

31. Keywords ribulose bisphosphate carboxylase small subunit （ rbcS ）;post transcriptional gene silencing （PTGS）;

二磷酸核酮糖羧化酶/加氧酶小亚基;转录后基因沉默;

32. Several possible mechanisms have been presented to explain the mechanism of trans-gene silencing, such as RNA threshold, aberrant RNA and ectopic pairing model and double-strand RNA model.

人们目前用以下几种模型来解释转录后水平基因沉默的机制，如RNA阈值模型、异常RNA和异位配对模型及双链RNA模型。

33. Man goes into the noisy crowed to drown his own clamour of silenc.

人走进喧哗的群众里去，为的是要淹没他自己的沉默的呼号。

34. A 1953 expose of the country's leading columnist of the 1930s and 1940s, Walter Winchell, brought Stuart fame and lawsuits aimed at silencing him.

他1953年对美国1930年代和1940年代著名专栏作家沃尔特温切尔的揭露给他 带来名声也惹来官司，对方想通过官司封住他的嘴。

35. “MGMT silencing is currently being used as a prognostic indicator of successful alkylation chemotherapy for glioblastoma;

他们写到：“目前使用MGMT沉默现象来作为预测烷基化化疗治疗胶质母细胞瘤预后效果的指标；

36. He can get maybe one off during his bubble, but he shouldn't get any more than that.You need to be Kicking, Gouging, Silencing, etc. at the END of casts for this to go smoothly.

他可能能够在开无敌的时候加上一次，但是他不应该能加得更多。

37. Keywords Low-frequency resonance Silencing box Exhaust noise;

低频共振;消声箱;排气噪声;

38. Here, all kinds of suppress mechanisms and application about RNA silencing were summarized in order to make people take cognizance of the disadvantage of RNA silencing technology while using it.

全面总结抑制RNA沉默机制及其应用，从而使人们充分认识到使用RNA沉默技术时应考虑到存在的不利因素。

39. Influence of Silencing Groove Geometry on Discharging Flow within Steering Vane Pump

减振槽型式对转向叶片泵瞬时流量的影响

40. Influence of silencing groove geometry on pressure transient within steering vane pump

减振槽型式对转向叶片泵配流冲击的影响

41. Generation of a rice mutant library by shotgun antisense gene silencing and mutant screening

利用反义基因沉默策略构建水稻突变体库及突变体筛选

42. Strangulate -- Depletes all Runic Power, dealing minor damage and silencing the target for up to 5 seconds. (Curse.com

勒颈：消耗所有符文能量，造成少量伤害，但会沉默目标，至多5秒。

43. Even an important function such as silencing the ringer is often beyond the expertise of average phone users.

即使是有些重要的功能，比如静音，也经常超出了普通使用者的能力。

44. It is no use silencing opposition.

压制反对意见是无济于事的。

45. It's no use silencing opposition.

压制反对意见是无济於事的。

46. silencing all criticism

压制所有的批评

47. silencing all criticism; silenced their opponents.

压制所有的批评；压制他们的反对者

48. Nipping conflict in the bud by silencing dark propaganda would do a lot of good.

压制黑暗宣传，以达到把冲突扼杀在萌芽中的目的，这会有很大益处。

49. The Function of Double-Stranded RNA in Gene Silencing

双链RNA在基因沉默中的作用

50. Possibly: Mutations that impair RNA silencing in Caenorhabditis elegans result in the mobilization of transposable elements.

可能是：突变，损害RNA沉默在秀丽新杆线虫，结果在动员的转座因子。

51. Peer argued the complicit action of international Internet companies is contributing to the silencing of Web media and urges these organisations to apply pressure to Chinese authorities.

同侪辩称，该共犯的行动，国际互联网公司是向沉默的网络媒体，并敦促这些组织施加压力，以中国当局。

52. Silencing is different from muting in that muting only affects what you hear, while silencing filters the player out for everyone in the channel.

和消音不同的是，消音只针对你有效(如同忽略名单)，但是保持频道静默，会使得该玩家在频道中的发言，别人完全听不到。

53. PRESSURE DEPENDENCE OF JET NOISE AND SILENCING OF BLOW-OFFS

喷注噪声的压力关系和排空降噪

54. Hence, we investigated whether RNA-dependent DNA methylation might operate in human cancers to mediate epigenetic silencing using the endogenous gene CDH1 as a potential target.

因此，我们用内源的CDH1基因作为可能的靶基因研究RNA依赖的DNA甲基化是否也在人类的癌症中参与了对基因的转录沉默。

55. In TGS in plants, cytoplasmic dsRNA containing promoter sequences is able to direct the silencing, and de novo methylation, of the homologous DNA.

在TGS的植物中，细胞质的双链RNA含有启动子序列，是能够直接沉默，和去甲基化，同源的DNA 。

56. In an LPS -model of ethanol -mediated liver injury, a similar dose of liposome- encapsulated TJU -2755 reduced liver injury by 60%. Similar to S -ODNs, siRNAs, are also gaining ground as highly efficient genc silencing agents.

在乙醇诱导的肝损伤LPS模型中,相似剂量脂质体包被的TJU-2755可减轻肝损伤达60%,与S-ODNs和siRNAs一样,已经成为高效的基因沉默剂。

57. At these pre-decision stages, apparently opposing chromatin structures may coexist on a gene locus but resolve in subsequent stages into exclusively activating or silencing structures (Fig. 1).

在前决定阶段里，明显的反向的染色质结构可能共同存在基因位点，但是在后来的阶段分解成专有的具有活性或沉默的结构。

58. Implement of Barley Stripe Mosaic Virus-based Induced Gene Silencing in Wheat

在小麦上实施大麦条斑病毒诱导的基因沉默

59. The former approach is technically simpler in mice but less promising in some ways: for example, cells that undergo silencing of the suicide gene are permanently un-killable.

在小鼠中，前一条途经在技术上较为简单，但是在某些情形下前途有限：例如，自杀基因沉默的细胞永远不能被杀死。

60. In Drosophila,the Ping-Pong model strongly suggests a post transcriptional component to transposon silencing.

在果蝇中，乒乓模式强烈地表明了是转座子沉默的一个后期转录组分。

61. Germ cell specific autosomal versions of several genes located on the X chromosome are activated during this period, thus circumventing the problem that would arise from their silencing .

在此期间，位于X染色体上的生殖细胞特有的染色体形式上的几个基因被激活，从而避免了因为它们的噪声抑制可能引起的问题。

62. This review introduces research progress on the mechanism of plant transgene silencing at transcriptional gene silencing (TGS) and post-transcriptional gene silencing (PTGS).

在此，从转录水平和转录后水平两个方面，综述了转基因植物中外源基因沉默的机制。

63. In every experiment, injection of double-stranded RNA carrying a genetic code led to silencing of the gene containing that particular code.

在每一次实验中，注射携带了一种遗传密码的双链RNA都导致了包含这种密码的基因的关闭。

64. Moreover,in the test of pressure transmission exhaust and silencing of noise,the material shows more properties of exhaust and noise elimination than the burnt copper powder.

在气压传动排气消声的测试中,与铜粉末烧结件相比具有更好的排气性能和消声性能。

65. Under the influence of French, Old English lost some of its inflections, acquired new words of Latin origin, and softened its pronunciation (blurring unstressed vowels and ultimately silencing the final e).

在法语影响下，古英语失去一些属折成份，增加新的拉丁语源同汇，语音软化(非重音元音含糊、尾元音e最后不发音)。

66. Development of Gene Expression and Gene Silencing Vectors Based onCotton Leaf Curl Virus for Functional Genomics in Cotton

基于抗卷叶病毒棉花基因组研究的基因表达和基因沉默载体的构建

67. Gene Silencing: A Novel Strategy of Adoptive Immunity

基因沉默:获得性免疫的新途径

68. Plant Transgene Silencing and the Presumable Mechanism of Plant Resistance to Virus

基因沉默与植物抗病毒的可能机制

69. Gene Silencing and Its Physiology Significance

基因沉默及其生理学意义

70. RNA induced silencing complex

基因沉默复合体

71. Gene silencing can be divided into two types: position effect and homology dependent gene silencing (HdGS).

基因沉默大体可以分为两类：位置效应引起的基因沉默和同源依赖的基因沉默。

72. Post-transcriptional gene silencing (PTGS) is an antiviral defense system of plants, which has led to a new understanding of the relationship between viruses and plants.

基因沉默的发现使得人们对植物和病毒的相互关系有了一个新的认识。

73. The mechanisms of gene silencing include copy numbers and configuration of transgene, integration sites in plant and transcription of transgene, etc.

基因沉默的机制是多方面的，包括转基因的拷贝数和构型、在植物上的整合位点、转基因的转录水平等。

74. From long period evolution with plants, plant virus obtains the ability to code gene silencing suppressors against this defense system.

基因沉默系统是植物抵抗病毒侵染的防卫体系，在长期的协同进化过程中，由病毒编码的抑制蛋白可以抵消基因沉默系统的作用。

75. gene-specific silencing

基因特异性沉默

76. Initiation and Silencing in Genomic Imprinting

基因组印迹的起动与沉默

77. Basic Strategy involves draining the mage, frost/flare, scattering rogue, silencing mage.

基本策略包括抽法师，冰霜/照明，驱散贼，沉默法师。

78. Keywords Ptn;PTEN;siRNA;gene silencing;gene;tumor suppressor;gene expression;transfection;

多效生长因子;PTEN;小干扰RNA;基因沉默;基因;肿瘤抑制;基因表达;转染;

79. "If you could prevent the silencing of the transgene or if you could purposefully silence something that you wanted inactivated, that could be a good thing.

如果你能阻止转基因沉默或者你能有目的的沉默你想使他失活的基因，这将是一个好消息。

80. What the media repeatedly claimed was her success in debate was predicated on her silencing of her male competitors, who were bullied into excess caution in dealing with a woman.

媒体反复宣扬的她在竞选辩论中的成功，是基于她对其男性竞争对手保持沉默的预言。而她的对手迫于外界的压力在处理女性的问题上过分谨慎。