tamoxifen
tamoxifen
1. I have read in the news that women with breast cancer should be taking anastrozole rather than tamoxifen,should I ask my doctor to change me to anastrozole .
15058657179嘉鹏健身器材有限公司：是生产游艺，娱乐，健身，休闲用品专用生产商。
2. August, 1994, surgery of lumpectomy and mastectomy, followed by Tamoxifen, expected by the doctor to have only one year to live.
1994年8月，行肿块切除及乳房切除术，紧接著使用三苯氧胺治疗，医生认为大约只可以再延续1年的生命。
3. 1998 Women at increased risk of developing breast cancer shown to reduce the chance of developing breast cancer by half by taking tamoxifen in the Breast Cancer Prevention Trial.
1998年,他莫昔芬乳腺癌预防试验表明高风险患者的发病机会降低一半.
4. Elemene may partially reverse the breast cancer tamoxifen drug-resistance, its reversal mechanism of drug-resistance concern with to decline apoptosis suppression protein bcl-2.
3. 榄香烯可部分逆转乳腺癌三苯氧胺耐药性，其逆转耐药机制可能与下调凋亡抑制蛋白Bcl-2有关。
5. more than 33,000 women participated in the Breast Cancer Prevention Trial (BCPT) and Study of Tamoxifen and Raloxifene (STAR).
33000多名女性参与了乳腺癌预防研究（BCPT）和他莫昔芬和雷洛昔芬的药物研究（STAR）。
6. Tamoxifen a roved by FDA for marketing as a treatment drug.
FDA批准他末昔芬作为治疗药物进入市场.
7. Tamoxifen has been given to women with breast cancer since 1974, usually after surgery to remove a tumor and in conjunction with chemotherapy.
Tamoxifen从1974年起被患乳腺痛的妇女使用，通常是在手术切除肿瘤后，配合化疗使用。
8. The effect of tamoxifen combined with medroxyprogesterone on the growth of cisplatin-resistant human epithelial ovarian cancer cell oine SKOV -3/DDP
TAM和MPA联合用药对卵巢癌顺铂耐药细胞株SKOV-3/DDP生长的影响
9. Tamoxifen inhibited the growth of ER-negtive and-positive brest cancer cells, induced G0/G1 phase arrest and induced cell apoptosis.
TAM能抑制ER阳性和阴性的乳腺癌细胞的生长,阻滞细胞周期于G0/G1期,并可诱导细胞凋亡;
10. You put her on tamoxifen?
|你给她服它莫西芬?
11. "We hae used a small molecule," he continued, "that binds to the resistant estrogen receptor, altering its conformation so that it now responds to tamoxifen in a more sensitie fashion.
“我们使用了一种结合在耐药的雌激素受体上的小分子，改变了该受体的结构，因此该受体可以更好了对阿莫西芬反应。
12. "Now we can also incorporate a woman's breast density to help inform the decision as to whether or not one should take tamoxifen," said Dr.
“现在我们也能够综合考虑妇女的乳房密度以决定是否使用它莫西芬。”
13. One study is a multinational adjuvant( post-operative) clinical trial evaluating disease-free and overall survival in women with breast cancer who take Femara after having remained disease-free with five years of tamoxifen therapy.
一项研究是多国辅药（后）床试验，用以评估乳癌患者服用弗隆后的无瘤生存率和整体生存率，这些女患者之前已进行了5年的他莫昔芬治疗，一直未发病。
14. Tamoxifen (TAM)
三苯氧胺
15. Keywords tamoxifen;breast cancer;resistance;
三苯氧胺;乳腺癌;耐药;
16. Keywords Tamoxifen;Phorbol ester;Cell;bre ast neoplasm;
三苯氧胺;佛波醇酯;细胞;乳腺肿瘤;
17. Keywords Tamoxifen Mifepristone Progesterone Termination of early pregnancy;
三苯氧胺;米非司酮;孕酮;抗早孕;
18. Keywords Tamoxifen;Fatty degeneration;Pathomorphology;
三苯氧胺;脂肪变性;病理形态学;
19. Keywords Tamoxifen;Non-small cell lung cancer;Chemotherapy;Resistance;
三苯氧胺;非小细胞肺癌;化学治疗;耐药;
20. Tamoxifen; Non-small cell lung cancer; Chemotherapy; Resistance
三苯氧胺;非小细胞肺癌;化学治疗；耐药
21. Tamoxifen competitively binds estrogen receptors.
三苯氧胺与雌激素受体结合力。
22. Tamoxifen can induce or exacerbate menopausal symptoms but reduces incidence of contralateral breast cancer and lowers serum cholesterol.
三苯氧胺会诱发或加重绝经期症状，但可减少对侧乳腺癌的发生率，降低血清胆固醇。
23. Effects of Tamoxifen On MCF-7 Human Breast Cancer Cell Cycle Kinetics
三苯氧胺对MCF-7人乳腺癌细胞系周期动力学影响
24. Effect of tamoxifen on mean pulmonary arterial pressure and IGF-1 in hypoxic rats
三苯氧胺对低氧性肺动脉高压大鼠平均肺动脉压与IGF-1的影响
25. Effects of Tamoxifen on the Secretory Function of Chorion and Decidua in Early Vitro Human Pregnancy
三苯氧胺对离体人早孕绒毛、蜕膜分泌功能的影响
26. Tamoxifen is the present clinical most commonly estrogen acceptor resistance, has become the estrogen acceptor positive breast cancer the golden standard of endocrine treatment.
三苯氧胺是目前临床最常用的雌激素受体拮抗剂，已成为激素受体阳性乳腺癌内分泌治疗的金标准。
27. Tamoxifen was the first estrogen modulator shown to increase surial and reduce the risk of breast cancer recurrence.
三苯氧胺是第一个雌激素调节剂，可增加患者的生存率和降低乳腺癌复发的危险。
28. The percentage of cancer stem cell related subpopulation(CD44+CD24-/low cells)in MCF-7 increases after treated with estradiol,and tamoxifen can decrease the percentage of cancer stem cells related subpopulation in MCF-7.
不同浓度E2作用下,MCF-7中肿瘤干细胞相关亚群含量增加,而在相同浓度的E2作用下,添加抗雌激素药物TAM能够使MCF-7中肿瘤干细胞相关亚群含量降低。
29. But while tamoxifen has been associated with side effects including an increased risk of uterine cancer, preliminary studies of raloxifene suggest it doesn't pose the same risk.
不过tamoxifen还有些副作用，包括增加子宫癌的危险。 初步研究结果表明，raloxifene没有这样的危险。
30. However, the consulting panel says, FDA needs consideration whether it is a necessity to make a genetic test before Tamoxifen is prescribed to the postmenstrual women.
不过，顾问小组说，医生在为绝经后女性开具他莫西芬这种处方药时，是否必须先作基因测试，仍需药管局再作考虑。
31. Unlike tamoxifen, aromatase inhibitors do not cause menopausal symptoms, but they may increase risk of osteoporosis.
与三苯氧胺不同的是，芳香抑制剂不会引起绝经期症状，但可增加骨质疏松症危险。
32. Breast density is primarily inherited, but hormone replacement therapy can increase density, while the breast cancer drug tamoxifen decreases it.
乳房的密度大小主要是遗传引起，但是激素替代治疗可以增加密度，而乳腺癌药物它莫西芬可以降低密度。
33. Pharmacy economic comparision analysis for the treatment of fibrocystic mastopathia with Rupixiao and tamoxifen
乳癖消与三苯氧胺治疗乳腺增生症的药物经济学分析
34. Breast Cancer Prevention Trial begins testing tamoxifen a cancer treatment drug as a preventive agent in women at increased risk of the disease.
乳腺癌预防试验开始证实治疗药物他莫昔芬在高风险女性人群中的预防作用.
35. Keywords Breast neoplasms;Tamoxifen;Hydralazine;Methylation;
乳腺肿瘤;三苯氧胺;肼苯哒嗪;甲基化;
36. Keywords Breast neoplasms;Receptors;estrogen;Deoxycytidine;Methylation;Tamoxifen;
乳腺肿瘤;受体;雌激素;脱氧胞苷;甲基化;三苯氧胺;
37. Keywords Breast neoplasms;Drug therapy;Cholecalciferol;Tamoxifen;
乳腺肿瘤;药物疗法;胆骨化醇;三苯氧胺;
38. Learn about certain medicines (i.e., tamoxifen, celecoxib) that may preent cancer.
了解你家庭成员的癌症史。
39. Related instructions are suggested to be added to the label of Tamoxifen to remind the breast cancer patients.
他们建议在他莫西芬的药品标签上添加相关说明，提醒乳腺癌患者。
40. Keywords Tamoxifen;Expanded skin;Stretch-back ratio;Fibrous capsule;
他莫昔芬;扩张皮瓣回缩率;纤维包膜;组织学;
41. Keywords Tamoxifen;Fatty liver;Pregnanediol;Pregnanetriol;Body mass index;
他莫昔芬;脂肪肝;孕烷二醇;孕烷三醇;人体质量指数;
42. Keywords Tamoxifen;Reversal;Neoplasms;multidrug resistance;
他莫昔芬;逆转;肿瘤;多药耐药;
43. Keywords Tamoxifen;Cisplatin;Human ovarian cancer;Proliferation;Cell cycle;
他莫昔芬;顺铂;卵巢癌细胞;增殖;细胞周期;
44. Tamoxifen reduced doxorubicin resistance in EAC/ADR cell in vitro
他莫昔芬体外降低EAC/ADR细胞对阿霉素的耐药性
45. Effects of tamoxifen on volume-activated Cl- currents of nasopharyngeal carcinoma cells at different stages of the cell cycle
他莫昔芬对不同生长周期鼻咽癌细胞容积激活性电流的作用
46. Influence of tamoxifen on bone mineral density of cancellated bone and compact bone in ovariectomized rats
他莫昔芬对去势大鼠松质骨及皮质骨骨密度的影响
47. Effect of tamoxifen on the immediate stretch-back rate of the expanded skin and the histopathology of fibrous capsule
他莫昔芬对扩张皮瓣即时回缩率及纤维包膜组织学的影响
48. Tamoxifen antagonized effect of estradiol,suggested that estradiol inhibited neointimal proliferation by estrogen receptor.
他莫昔芬拮抗雌二醇的作用，提示雌二醇通过受体抑制内膜增生。
49. An Experimental Study of the Inhibition of Tamoxifen on Rat Model of Benign Prostatic Hyperplasia
他莫昔酚对大鼠前列腺增生动物模型的抑制作用及机理研究
50. Tamoxifen, sold under the name Nolvadex, is a drug commonly used to treat breast cancer.
他莫西芬是一种治疗乳腺癌的常用药，目前以全国法医协会的名誉销售。
51. Tamoxifen, a drug that blocks the effects of estrogen on the body, is often used to treat women whose tumors are sensitie to estrogen.
他莫西芬是体内雌激素效应的抑制剂，常被用于治疗女性患者体内对雌激素敏感的肿瘤的治疗。
52. Howeer, tamoxifen is associated with increased risk of death from other causes, such as strokes and endometrial cancer.
但是三苯氧胺可以增加其他原因的死亡率，例如休克和子宫内膜癌等。
53. Tamoxifen has also been used recently.
但晚期需外科治疗。
54. "Physicians need not be overly concerned that treatment with tamoxifen will increase the risk for or exacerbate existing depression in women," the authors write.
作者写道：在采用他莫西芬治疗女性患者时，内科医师没有必要过度关注它会增加患抑郁症的危险，或会使抑郁症患者病情加重。
55. Keywords Prolactinoma;Estrogen antagonists;Tamoxifen;CH3 cells;
催乳素瘤;雌激素拮抗剂;他莫昔芬;CH3细胞;
56. Keywords Tamoxifen;MMP -2,9;Macrophage;Abdominal aortic aneurysm model;Inflammation;Elastic fiber;
关键词他莫昔芬;MMP-2;9;巨噬细胞;腹主动脉瘤模型;炎症;弹力纤维;
57. Keywords In vitro;Endocrine therapy;Breast cancer;Estrogen receptor（ER）;Patterns of five cell types;Tamoxifen;Megestrol acetate;
关键词体外;内分泌治疗;乳腺癌;雌激素受体;ER五型分类;三苯氧胺;醋酸甲地孕酮;
58. Of those, 96 were prescribed Tamoxifen, a drug therapy considered one of the best options for blocking the hormones that promote cancerous cell growth.
其中,96名患者正在服用三苯氧胺，这种药物治疗被认为是阻断促进癌细胞生长的激素的最佳方案之一。
59. Study of Chemotherapy with Tamoxifen for Treatment of Non-small Cell Lung Cancer
化疗结合三苯氧胺治疗非小细胞肺癌疗效分析
60. Clinical observation of chemotherapy combined with tamoxifen in treatment of patients with pulmonary carcinoma
化疗联合三苯氧胺治疗肺癌疗效观察
61. Meanwhile newer drugs that inhibit the aromatase enzyme, suppressing natural estrogen manufacture in the body, have proved superior to tamoxifen in postmenopausal women.
另一方面，有一种可抑制芳香酶从而阻止人体制造雌性素的新药，对停经后乳癌病患的效果又更胜于泰莫西芬。
62. Because the Irish study looked only at prescription records and not diagnoses, medical records, or the patients themseles, the researchers could not fully explore why women stopped taking tamoxifen.
因为爱尔兰的研究只是调查了处方记录，而不是诊断，医疗文件或患者本身，研究者不能完全的了解为什么妇女停止服用他莫西芬。
63. The objective response to antiestrogen tamoxifen (TAM)in advanced breast cancer with respect to its estrogen receptor (ER) Status was studied in 55 patients.
在55例晚期乳癌病人中研究了抗雌激素他莫昔芬(TAM)治疗效果和乳癌雌激素受体(ER)状态的关系。
64. The most common agent prescribed in this category is tamoxifen (also called Nolvadex).
在内分泌治疗中最常选用的药物是他莫西芬（三苯氧胺）。
65. Women who had used antidepressants in the year before starting tamoxifen were also more likely to quit (HR 1.41).
在开始使用他莫西芬前一年内使用过抗抑郁药的妇女也容易停药（风险比1.41）。
66. Study of High Dose Oral Tamoxifen Using a Potential Multidrug-Resistance-Reversal Agent in Refractory Patients with Non-Small Cell Lung Cancer
大剂量三苯氧胺提高非小细胞肺癌疗效的研究
67. If any cells show signs of the early mutations that lead to cancer, doctors can suggest the drug tamoxifen, which is believed to reduce the risk of breast cancer by suppressing precancerous cells.
如果有任何细胞呈现早期致癌的变异，医生可建议使用它莫西芬，这是一种有效抑制早期癌细胞的药，可减少癌病的发生。
68. Coombs RC, A randomized trial of exemstane after two or three years of tamoxifen therapy in postmenopausal women with primary breast cancer. N Engl J Med 2004; 350:1081-1092
孙燕、李丽庆、宋三泰等，注射用曲妥珠单抗治闻晚期乳腺癌临床验证报告。中华肿瘤杂志2003；1；581-583
69. Tamoxifen Modulates the Expression of Complement Inhibitory Proteins on Chorio-carcinoma Cell Line JAR
它莫西芬对绒毛膜癌细胞株JAR补体调节蛋白表达的影响
70. For women who don't go through early menopause, tamoxifen therapy can also shorten the window of opportunity to have children.
对于没有提早停经的女性来说，抗雌激素治疗也会减少生育孩童的机会。
71. For those who find out that they are at higher risk, the drugs tamoxifen and raloxifene may be options for lowering their risk.
对于那些发现自己处于高危险群的人，有tamoxifen以及raloxifene这两种药可选择，能降低她们的风险。
72. Although there are negative reports, NSABP B-16 and NSABP B-20 investigation all confirmed the advantage of regimen of AC, CMF combined with Tamoxifen.
尽管对三苯氧胺与细胞毒性药物联合应用有否定的研究结论，NSABP B-16试验和NSABP B-20试验分别肯定了AC方案和CMF方案与三苯氧胺联用的优势。
73. The risk was highest for local and regional recurrence. These results held regardless of tamoxifen treatment, suggesting that adjuant radiation treatment was highly effectie.
局限性复发的风险是最高的。不考虑三苯氧胺治疗，已有的结果表明辅助放疗是非常有效的。
74. Women aged 35 to 44 years and those oer age 75 years were most likely to quit tamoxifen (hazard ratios [HR] 1.36 and 1.46, respectiely).
年龄在35到44岁和超过75岁的妇女最可能停止服用他莫西芬（风险比分别为1.36和1.46）。
75. Object:The effect of tamoxifen (TAM) was evaluated on a mammary tumor model induced by 7.12-dimethylbenz(a)anthracene (DMBA) in the female Sprague-Dawley(SD) rats.
应用DMBA诱发的雌性SD大鼠乳腺癌模型，初步探讨了大鼠乳腺受致癌剂作用后，三苯氧胺对乳腺癌发生的影响。
76. Identification of Genes Involved in the Action of Tamoxifen and Estrogen in the Human Breast Cancer Cells Using Microarray and Real-time PCR Analysis
应用基因芯片（Microarray）和实时监测聚合酶链反应（Real-time PCR）技术检测他莫昔芬和雌二醇对人类乳腺癌细胞基因表达的调控
77. Novartis is further evaluating Femara compared to tamoxifen in the adjuvant setting.
弗隆用作辅助药时，诺华以他莫昔芬为对照，对它做了进一步的评估。
78. Coombes RC,Hall E,Gibson LJ,et al.A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer.N Engl J Med, 2004,350:1081.
张少华,江泽飞,宋三泰,等.泰索帝联合希罗达治疗蒽环类化疗失败复发转移性乳腺癌的临床研究.癌症进展,2004,2:217-220.
79. Anti-estrogen drugs such as tamoxifen (Noaldex) are a standard treatment for hormone-dependent breast cancer.
抗雌激素**物如他莫昔酚是激素依赖性乳癌的标准治疗。
80. Anti-estrogen drugs such as tamoxifen (Novaldex) are a standard treatment for hormone-dependent breast cancer.
抗雌激素药物如他莫昔酚是激素依赖性乳癌的标准治疗。
